Furrows S J, McCroddan J, Bligh W J, Chiodini P
Department of Clinical Parasitology, Hospital for Tropical Diseases, Mortimer Market, Capper Street, London, UK.
Clin Microbiol Infect. 2006 May;12(5):459-62. doi: 10.1111/j.1469-0691.2006.01381.x.
Diagnosis of the parasitic infection cysticercosis is usually confirmed by serological assays. The electroimmunotransfer blot (EITB) for cysticercosis is a sensitive and specific assay, which uses six glycoprotein antigens on a strip to detect antibodies to Taenia solium cysticerci. Although the appearance of bands at any of these six sites is considered to be a positive result, a growing body of evidence suggests that the presence of a single 50-kDa band in this assay may not indicate infection. An audit of 984 samples tested over a 3-year period showed that only two (15.4%) of 13 samples with a single 50-kDa band were associated with a diagnosis of cysticercosis. Possible reasons for this include technical problems, cross-reactivity with other parasites or other diseases, or the presence of a non-specific band. The results suggest that the finding of a single 50-kDa band should be interpreted with caution.
寄生虫感染囊尾蚴病的诊断通常通过血清学检测来确诊。囊尾蚴病的电免疫转移印迹法（EITB）是一种灵敏且特异的检测方法，它使用条带上的六种糖蛋白抗原检测针对猪带绦虫囊尾蚴的抗体。尽管在这六个位点中的任何一个出现条带都被视为阳性结果，但越来越多的证据表明，该检测中单一50 kDa条带的出现可能并不表明感染。对三年内检测的984份样本进行的一项审查显示，在13份仅有单一50 kDa条带的样本中，只有两份（15.4%）与囊尾蚴病诊断相关。其可能原因包括技术问题、与其他寄生虫或其他疾病的交叉反应，或存在非特异性条带。结果表明，对于单一50 kDa条带的检测结果应谨慎解读。
