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巴勒斯坦加沙地带体外受精中心不孕女性中弓形虫、巨细胞病毒、风疹病毒和沙眼衣原体的血清流行率。

Seroprevalence of Toxoplasma gondii, cytomegalovirus, rubella virus and Chlamydia trachomatis among infertile women attending in vitro fertilization center, Gaza strip, Palestine.

作者信息

Al-Hindi Adnan, Al-Helou Tharwat, Al-Helou Yousef

机构信息

The Islamic University of Gaza, Faculty of Science, Department of Biology, P.O.Box 108, Gaza, Palestine.

出版信息

J Egypt Soc Parasitol. 2010 Aug;40(2):451-8.

PMID:21246952
Abstract

In the present study, the seroprevalence of Toxoplasmia gondii, rubella, cytomegalovirus (CMV) and Chlamydia trachomatis in Palestinian women was determined through antenatal screening. The study included 1954 Palestinian women records which were reviewed and analyzed statistically from 2000-2005. Those women attended In vitro fertilization center in Gaza complaining from infertility and abortion. Anti-Toxoplasma, anti-rubella, anti-CMV and anti-Chlamydia IgM antibodies were assayed using an enzyme linked immunosorbent assay (ELISA). Positive results were found in 7.9%, 6%, 7% and 12.8% for T. gondii, CMV, Rubella and C. trachomatis antibodies. A high significant infection rate was observed in year 2003 (P = 0.001) for T. gondii. A clear variation with statistical significance was observed in the seroprevalence for all the studied pathogens regarding year of collection and age of women. The study indicated that T. gondii, rubella, CMV and C. trachomatis are still constitute a public health problem among pregnant women and considered one of the abortion factors.

摘要

在本研究中,通过产前筛查确定了巴勒斯坦妇女弓形虫、风疹、巨细胞病毒(CMV)和沙眼衣原体的血清流行率。该研究纳入了1954名巴勒斯坦妇女的记录,这些记录来自2000年至2005年,并进行了回顾和统计分析。这些妇女前往加沙的体外受精中心,抱怨存在不孕和流产问题。使用酶联免疫吸附测定(ELISA)检测抗弓形虫、抗风疹、抗CMV和抗沙眼衣原体IgM抗体。弓形虫、CMV、风疹和沙眼衣原体抗体的阳性结果分别为7.9%、6%、7%和12.8%。2003年观察到弓形虫的感染率极高(P = 0.001)。在所有研究病原体的血清流行率方面,观察到采集年份和妇女年龄存在明显的统计学差异。该研究表明,弓形虫、风疹、CMV和沙眼衣原体仍然是孕妇中的公共卫生问题,并且被认为是流产因素之一。

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