Ishizu K, Yoshihiro S, Joko K, Takihara H, Sakatoku J, Tanaka K
Department of Urology, Nagato General Hospital.
Hinyokika Kiyo. 1991 Sep;37(9):1057-60.
A 79-year-old man complained of pollakisuria and sense of retention. The prostate was stony hard and heterogeneously enhanced on computed tomographic (CT) scan. The serum levels of prostatic specific antigen, prostatic acid phosphatase and gamma-Seminoprotein were abnormally high. Prostatic biopsy showed mucinous adenocarcinoma which was stained by prostatic specific antigen. Bone scintigraphy revealed multiple metastases. Hormonal therapy was performed. Each prostatic tumor marker decreased to the normal range within 2 months. After 3 months, the prostate was almost normalized on digital examination and CT scan. There were no new metastases, prostatic biopsy revealed that most cancer cells had degenerated to nonviable cells and bone metastases had decreased.
一名79岁男性主诉尿频和尿潴留感。前列腺坚硬如石，在计算机断层扫描（CT）上呈不均匀强化。前列腺特异性抗原、前列腺酸性磷酸酶和γ-精浆蛋白的血清水平异常升高。前列腺活检显示为黏液腺癌，可被前列腺特异性抗原染色。骨闪烁显像显示多处转移。进行了激素治疗。每种前列腺肿瘤标志物在2个月内降至正常范围。3个月后，直肠指检和CT扫描显示前列腺几乎恢复正常。没有新的转移灶，前列腺活检显示大多数癌细胞已退化为无活力细胞，骨转移减少。
