飞龙掌血中的生物碱。

Alkaloids from Toddalia aculeata.

作者信息

Jain Subhash C, Pandey Mukesh K, Upadhyay Ravi K, Kumar Rohtash, Hundal Geeta, Hundal Maninder S

机构信息

Department of Chemistry, University of Delhi, Delhi 110 007, India.

出版信息

Phytochemistry. 2006 May;67(10):1005-10. doi: 10.1016/j.phytochem.2006.03.012. Epub 2006 May 2.

DOI:10.1016/j.phytochem.2006.03.012

PMID:16647728

Abstract

Two alkaloids N-methyl-4-hydroxy-7-methoxy-3-(2,3-epoxy-3-methylbutyl)-1H-quinolin-2-one (1) and 3-(2,3-dihydroxy-3-methylbutyl)-4,7-dimethoxy-1-methyl-1H-quinolin-2-one (2a) have been isolated from CH(2)Cl(2):methanol (1:1) and methanol extracts of leaves and stems of Toddalia aculeata. Their structures along with that of 15 other compounds, of which three are isolated for the first time from genus Toddalia, were established by their detailed spectral studies including 2D NMR viz. (1)H-(1)H COSY, (1)H-(13)C COSY, and HMBC.

摘要

从飞龙掌血叶和茎的二氯甲烷

甲醇（1:1）提取物及甲醇提取物中分离得到了两种生物碱，即N-甲基-4-羟基-7-甲氧基-3-(2,3-环氧-3-甲基丁基)-1H-喹啉-2-酮（1）和3-(2,3-二羟基-3-甲基丁基)-4,7-二甲氧基-1-甲基-1H-喹啉-2-酮（2a）。通过详细的光谱研究，包括二维核磁共振谱（如1H-1H COSY、1H-13C COSY和HMBC），确定了它们以及其他15种化合物的结构，其中有3种是首次从飞龙掌血属中分离得到的。