Zeng Zhi, Tian Rui, Feng Jia, Yang Nian-An, Yuan Lin
Hubei Provincial Key Laboratory of Occurrence and Intervention of Rhumatic Disease, Hubei Minzu University, Enshi 445000, China.
Saudi Pharm J. 2021 Aug;29(8):781-798. doi: 10.1016/j.jsps.2021.05.003. Epub 2021 May 20.
(L.) Lam., belonging to genus of Rutaceae family, is a folk medicine in China used for hundreds of years. The whole plant can be used as medicine, especially the root that used to be applied in the folk. In recent decades, with the in-depth research from domestic and foreign researchers, it has gradually been discovered that the chemical components in are mainly coumarins and alkaloids. Its pharmacological effects are manifested in anti-inflammatory and analgesic, hemostatic coagulation, anti-tumor, treatment of cardiovascular diseases, etc. It has a wide range of clinical applications and significant effects on rheumatism, pain, wound bleeding, and bruises. Due to its important research value, in this article, the chemical compositions and pharmacological effects of are comprehensively expounded in recent years in order to provide a reference for the related research and application of this medicinal material, which were carried out through a bibliometric search using the Science Citation Index- Expanded (SCIE) database, web of science, Google scholar and Chinese National Knowledge Infrastructure (CNKI) and all that.
（L.）Lam. 属于芸香科属，是中国一种使用了数百年的民间药物。全株均可入药，尤其是根部在民间常被应用。近几十年来，随着国内外研究人员的深入研究，逐渐发现其化学成分主要为香豆素和生物碱。其药理作用表现为抗炎镇痛、止血凝血、抗肿瘤、治疗心血管疾病等。它在临床上有广泛应用，对风湿、疼痛、伤口出血和瘀伤有显著疗效。由于其重要的研究价值，本文通过使用科学引文索引扩展版（SCIE）数据库、科学网、谷歌学术和中国知网等进行文献计量检索，对近年来其化学成分和药理作用进行了全面阐述，以便为该药材的相关研究和应用提供参考。
