Sandström Falk Marie Helen, Faergemann Jan
Department of Dermatology, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden.
Acta Derm Venereol. 2006;86(2):135-9. doi: 10.2340/00015555-0040.
There is limited knowledge of the prognosis in adult atopic dermatitis. We previously published a long-term follow-up questionnaire study of adults with atopic dermatitis. This study is a clinical examination of 79 adults (mean age 57 years) recruited 3 years after that study. Most patients (68%) still reported that they had atopic dermatitis and 53% had ongoing eczema at examination, mainly located on the head and neck. Severity was mainly mild to moderate, but 12% had severe atopic dermatitis. IgE antibodies to Malassezia (m70) were more common in patients with ongoing atopic dermatitis, while positive Malassezia culture was seen mainly in patients with no ongoing atopic dermatitis. M. obtusa and M. globosa were the most commonly cultured Malassezia species. In conclusion, considering increased prevalence of atopic dermatitis in children in recent decades and the fact that atopic dermatitis in most adults continues for many years, we should expect to see more adults with atopic dermatitis in the future.
关于成人特应性皮炎的预后，目前了解有限。我们之前发表过一项针对成人特应性皮炎患者的长期随访问卷调查研究。本研究是在该研究3年后对79名成年人（平均年龄57岁）进行的临床检查。大多数患者（68%）仍报告患有特应性皮炎，53%的患者在检查时有持续性湿疹，主要位于头颈部。严重程度主要为轻度至中度，但12%的患者患有重度特应性皮炎。马拉色菌（m70）的IgE抗体在患有持续性特应性皮炎的患者中更为常见，而马拉色菌培养阳性主要见于无持续性特应性皮炎的患者。钝形马拉色菌和球形马拉色菌是最常培养出的马拉色菌种。总之，鉴于近几十年来儿童特应性皮炎的患病率上升，以及大多数成人特应性皮炎会持续多年这一事实，我们预计未来会看到更多的成人特应性皮炎患者。
