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管花肉苁蓉中的单萜类成分——管花苷A-E及管花醇的化学结构

Monoterpene constituents from Cistanche tubulosa--chemical structures of kankanosides A-E and kankanol-.

作者信息

Xie Haihui, Morikawa Toshio, Matsuda Hisashi, Nakamura Seikou, Muraoka Osamu, Yoshikawa Masayuki

机构信息

Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8412, Japan.

出版信息

Chem Pharm Bull (Tokyo). 2006 May;54(5):669-75. doi: 10.1248/cpb.54.669.

DOI:10.1248/cpb.54.669
PMID:16651763
Abstract

Four new iridoid glycosides, kankanosides A (1), B (2), C (3), and D (4), a chlorinated iridoid, kankanol (5), and an acyclic monoterpene glycoside, kankanoside E (6), were isolated from the methanolic extract of dried stems of Cistanche tubulosa (SCHRENK) R. WIGHT (Orobanchaceae) together with 16 known compounds. The structures of these new compounds (1-6) were determined on the basis of the chemical and physicochemical evidence.

摘要

从管花肉苁蓉(列当科)干燥茎的甲醇提取物中分离得到4个新的环烯醚萜苷类化合物,即管花苷A(1)、B(2)、C(3)和D(4),1个氯化环烯醚萜管花醇(5),以及1个无环单萜苷管花苷E(6),同时还分离得到16个已知化合物。通过化学和物理化学证据确定了这些新化合物(1 - 6)的结构。

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引用本文的文献

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Analysis of the active ingredients and health applications of cistanche.肉苁蓉有效成分及健康应用分析。
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Herba Cistanche (Rou Cong-Rong): One of the Best Pharmaceutical Gifts of Traditional Chinese Medicine.肉苁蓉:中药最出色的馈赠之一。
Front Pharmacol. 2016 Mar 1;7:41. doi: 10.3389/fphar.2016.00041. eCollection 2016.
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Ethnomedicinal and phytochemical review of Pakistani medicinal plants used as antibacterial agents against Escherichia coli.
巴基斯坦用作抗大肠杆菌抗菌剂的药用植物的民族药用和植物化学综述。
Ann Clin Microbiol Antimicrob. 2014 Aug 19;13:40. doi: 10.1186/s12941-014-0040-6.
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Acylated phenylethanoid glycosides, echinacoside and acteoside from Cistanche tubulosa, improve glucose tolerance in mice.肉苁蓉中的酰化苯乙醇苷类化合物,毛蕊花糖苷和麦角甾苷,可改善小鼠的葡萄糖耐量。
J Nat Med. 2014 Jul;68(3):561-6. doi: 10.1007/s11418-014-0837-9. Epub 2014 Apr 19.
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Short synthesis of the common trisaccharide core of kankanose and kankanoside isolated from Cistanche tubulosa.从管花肉苁蓉中分离得到的堪萨斯糖和堪萨斯糖苷的常见三糖核心的短合成。
Beilstein J Org Chem. 2013 Apr 11;9:705-9. doi: 10.3762/bjoc.9.80. Print 2013.