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氧自由基的直接和间接测量

Direct and indirect measurements of oxygen radicals.

作者信息

Saran M, Bors W

机构信息

GSF-Forschungszentrum für Umwelt und Gesundheit, Neuherberg.

出版信息

Klin Wochenschr. 1991 Dec 15;69(21-23):957-64. doi: 10.1007/BF01645139.

DOI:10.1007/BF01645139
PMID:1665887
Abstract

Instead of covering the available detection methods in detail it is attempted to highlight the ambiguities inherent in oxygen radical detection under in vivo conditions. Due to physicochemical properties of the oxygen molecule, all organic matter is bound to autoxidize. From this it follows that a certain 'background' level of oxygen radical production will always be present and that it may be difficult to differentiate between inherent and induced oxygen radical production. Radicals by their very nature react 'unspecifically'. This infers that it is difficult to identify them unequivocally. The most common methods for oxygen radical detection are briefly mentioned.

摘要

本文并非详细介绍现有的检测方法,而是试图突出体内条件下氧自由基检测中固有的模糊性。由于氧分子的物理化学性质,所有有机物都会自动氧化。由此可知,氧自由基产生的一定“背景”水平将始终存在,并且可能难以区分固有产生和诱导产生的氧自由基。自由基因其本质会进行“非特异性”反应。这意味着很难明确识别它们。文中简要提及了氧自由基检测的最常用方法。

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