1924年至1974年间代谢控制的概念发展
Conceptual developments in metabolic control, 1924-1974.
作者信息
Beevers H
机构信息
Thimann Laboratories, University of California, Santa Cruz, California 95064.
出版信息
Plant Physiol. 1974 Oct;54(4):437-42. doi: 10.1104/pp.54.4.437.
Abstract
A brief sketch is given of the development of the understanding of the respiratory mechanism in plants over the past 50 years. Against this background the following aspects of control are discussed: (a) nonreversibility of catabolic sequences; (b) compartmentation of reactions and reactants; (c) control by amount of enzyme; (d) control by NAD and NADP; (e) control by ADP supply; (f) pacemaker reactions in glycolysis; and (g) control at branch points: further examples of allostery.
摘要
本文简要概述了过去50年里对植物呼吸机制认识的发展。在此背景下，讨论了以下控制方面：（a）分解代谢序列的不可逆性；（b）反应和反应物的区室化；（c）酶量控制；（d）NAD和NADP控制；（e）ADP供应控制；（f）糖酵解中的起搏器反应；以及（g）分支点处的控制：变构的更多实例。
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