羽扇豆叶片叶绿体中喹诺里西啶生物碱生物合成酶的定位。
Localization of the Enzymes of Quinolizidine Alkaloid Biosynthesis in Leaf Chloroplasts of Lupinus polyphyllus.
机构信息
Institut für Pharmazeutische Biologie der Technischen Universität Braunschweig, D-3300 Braunschweig, West Germany.
出版信息
Plant Physiol. 1982 Jul;70(1):74-7. doi: 10.1104/pp.70.1.74.
Abstract
Studies with purified chloroplasts of Lupinus polyphyllus LINDL. leaflets indicate that the first two enzymes of quinolizidine alkaloid biosynthesis, lysine decarboxylase and 17-oxosparteine synthase, are localized in the chloroplast stroma. Thus, both enzymes share the same subcellular compartment as the biosynthetic pathway of lysine, the precursor of quinolizidine alkaloids. The activity of diaminopimelate decarboxylase, the final enzyme in lysine biosynthesis, is about two to three orders of magnitude higher than that of the enzymes of alkaloid formation.
摘要
对羽扇豆小叶的纯化叶绿体进行的研究表明，喹啉生物碱生物合成的前两个酶，赖氨酸脱羧酶和 17-氧代高丝氨酸合酶，定位于叶绿体基质中。因此，这两种酶与赖氨酸生物合成途径共享相同的亚细胞区室，赖氨酸是喹啉生物碱的前体。赖氨酸生物合成的最后一个酶二氨基庚二酸脱羧酶的活性比生物碱形成酶的活性高两到三个数量级。
相似文献
1
Localization of the Enzymes of Quinolizidine Alkaloid Biosynthesis in Leaf Chloroplasts of Lupinus polyphyllus.羽扇豆叶片叶绿体中喹诺里西啶生物碱生物合成酶的定位。
Plant Physiol. 1982 Jul;70(1):74-7. doi: 10.1104/pp.70.1.74.
2
Activation of chloroplast-localized enzymes of quinolizidine alkaloid biosynthesis by reduced thioredoxin.还原型硫氧还蛋白激活质体定位的喹诺里西啶生物碱生物合成酶。
Plant Cell Rep. 1981 Aug;1(1):6-9. doi: 10.1007/BF00267646.
3
A chloroplast-localized lysine decarboxylase of Lupinus polyphyllus: the first enzyme in the biosynthetic pathway of quinolizidine alkaloids.多叶羽扇豆的一种定位于叶绿体的赖氨酸脱羧酶：喹诺里西啶生物碱生物合成途径中的首个酶。
FEBS Lett. 1980 Jun 16;115(1):35-8. doi: 10.1016/0014-5793(80)80721-6.
4
New Analytical Approach to Quinolizidine Alkaloids and Their Assumed Biosynthesis Pathways in Lupin Seeds.新型喹诺里西啶生物碱分析方法及其在羽扇豆种子中假定生物合成途径。
Toxins (Basel). 2024 Mar 21;16(3):163. doi: 10.3390/toxins16030163.
5
Microclimatic variation in UV perception and related disparity in tropane and quinolizidine alkaloid composition of Atropa acuminata, Lupinus polyphyllus and Hyoscyamus niger.尖叶颠茄、多叶羽扇豆和黑莨菪在紫外线感知方面的微气候变异以及托烷和喹诺里西啶生物碱成分的相关差异。
J Photochem Photobiol B. 2016 Aug;161:230-5. doi: 10.1016/j.jphotobiol.2016.04.028. Epub 2016 Apr 30.
6
Quinolizidine alkaloid biosynthesis: recent advances and future prospects.喹诺里西啶生物碱生物合成：最新进展与未来展望。
Front Plant Sci. 2012 Oct 26;3:239. doi: 10.3389/fpls.2012.00239. eCollection 2012.
7
A model mechanism for the enzymatic synthesis of lupin alkaloids.羽扇豆生物碱酶促合成的模型机制。
Z Naturforsch C Biosci. 1979 Sep-Oct;34(9-10):704-8. doi: 10.1515/znc-1979-9-1009.
8
Transcript profiling of a bitter variety of narrow-leafed lupin to discover alkaloid biosynthetic genes.窄叶羽扇豆苦味品种的转录组分析，以发现生物碱生物合成基因。
J Exp Bot. 2017 Nov 28;68(20):5527-5537. doi: 10.1093/jxb/erx362.
9
Subcellular Localization of Enzymes Involved in Indole Alkaloid Biosynthesis in Catharanthus roseus.长春花中参与吲哚生物碱生物合成的酶的亚细胞定位。
Plant Physiol. 1987 Dec;85(4):1099-102. doi: 10.1104/pp.85.4.1099.
10
Cadaverine--pyruvate transamination: the principal step of enzymatic quinolizidine alkaloid biosynthesis in Lupinus polyphyllus cell suspension cultures.尸胺 - 丙酮酸转氨基作用：多叶羽扇豆细胞悬浮培养物中喹诺里西啶生物碱酶促生物合成的主要步骤。
FEBS Lett. 1979 May 15;101(2):343-6. doi: 10.1016/0014-5793(79)81040-6.
引用本文的文献
1
Genomic structure of yellow lupin (Lupinus luteus): genome organization, evolution, gene family expansion, metabolites and protein synthesis.黄羽扇豆（Lupinus luteus）的基因组结构：基因组组织、进化、基因家族扩张、代谢产物与蛋白质合成
BMC Genomics. 2025 May 14;26(1):477. doi: 10.1186/s12864-025-11678-8.
2
The aerial epidermis is a major site of quinolizidine alkaloid biosynthesis in narrow-leafed lupin.地上表皮是窄叶羽扇豆中喹诺里西啶生物碱生物合成的主要部位。
New Phytol. 2025 Mar;245(5):2052-2068. doi: 10.1111/nph.20384. Epub 2025 Jan 14.
3
A Bitter-Sweet Story: Unraveling the Genes Involved in Quinolizidine Alkaloid Synthesis in .一个苦乐参半的故事：解析[具体植物名称]中喹诺里西啶生物碱合成所涉及的基因 。
需注意，原文中“in.”后面应该有具体植物名称，但这里未完整给出。
Front Plant Sci. 2022 Jan 26;12:795091. doi: 10.3389/fpls.2021.795091. eCollection 2021.
4
Analysis of Genetic Diversity in the Traditional Chinese Medicine Plant 'Kushen' ( Ait.).中药植物“苦参”（Ait.）的遗传多样性分析
Front Plant Sci. 2021 Aug 3;12:704201. doi: 10.3389/fpls.2021.704201. eCollection 2021.
5
Expression Profiles of Alkaloid-Related Genes across the Organs of Narrow-Leafed Lupin ( L.) and in Response to Anthracnose Infection.窄叶羽扇豆（L.）各器官生物碱相关基因的表达谱及其对炭疽病感染的响应。
Int J Mol Sci. 2021 Mar 6;22(5):2676. doi: 10.3390/ijms22052676.
6
Quinolizidine and Pyrrolizidine Alkaloid Chemical Ecology - a Mini-Review on Their Similarities and Differences.喹诺里西啶和吡咯里西啶生物碱化学生态学——关于它们异同点的小型综述
J Chem Ecol. 2019 Feb;45(2):109-115. doi: 10.1007/s10886-018-1005-6. Epub 2018 Aug 6.
7
Mini review on photosensitization by plants in grazing herbivores.关于放牧食草动物中植物光敏化的简短综述。
Trop Anim Health Prod. 2018 Jun;50(5):925-935. doi: 10.1007/s11250-018-1583-x. Epub 2018 Apr 6.
8
Quinolizidine Alkaloid Biosynthesis in Lupins and Prospects for Grain Quality Improvement.羽扇豆中喹诺里西啶生物碱的生物合成及改善籽粒品质的前景
Front Plant Sci. 2017 Jan 31;8:87. doi: 10.3389/fpls.2017.00087. eCollection 2017.
9
Inhibition of seed germination by quinolizidine alkaloids : Aspects of allelopathy in Lupinus albus L.喹诺里西啶生物碱对种子萌发的抑制：白羽扇豆（ Lupinus albus L.）化感作用的一些方面
Planta. 1983 Aug;158(4):365-8. doi: 10.1007/BF00397339.
10
Turnover and transport of quinolizidine alkaloids. Diurnal fluctuations of lupanine in the phloem sap, leaves and fruits of Lupinus albus L.羽扇豆醇生物碱的转移和运输。羽扇豆醇在白羽扇豆韧皮部汁液、叶片和果实中的日变化。
Planta. 1984 Nov;161(6):519-24. doi: 10.1007/BF00407083.
本文引用的文献
1
Slow Passive Diffusion of Orthophosphate between Intact Isolated Chloroplasts and Suspending Medium.正磷酸盐在完整分离叶绿体与悬浮介质之间的缓慢被动扩散
Plant Physiol. 1981 Mar;67(3):470-3. doi: 10.1104/pp.67.3.470.
2
[The biosynthesis of sparteine].[鹰爪豆碱的生物合成]
Arch Pharm Ber Dtsch Pharm Ges. 1961 Oct;294/66:610-5. doi: 10.1002/ardp.19612941003.
3
A chloroplast-localized lysine decarboxylase of Lupinus polyphyllus: the first enzyme in the biosynthetic pathway of quinolizidine alkaloids.多叶羽扇豆的一种定位于叶绿体的赖氨酸脱羧酶：喹诺里西啶生物碱生物合成途径中的首个酶。
FEBS Lett. 1980 Jun 16;115(1):35-8. doi: 10.1016/0014-5793(80)80721-6.
4
The enzymology of lysine biosynthesis in higher plants: complete localization of the regulatory enzyme dihydrodipicolinate synthase in the chloroplasts of spinach leaves.高等植物赖氨酸生物合成的酶学：调节酶二氢二吡啶二羧酸合酶在菠菜叶片叶绿体中的完全定位。
FEBS Lett. 1980 Jul 28;116(2):189-92. doi: 10.1016/0014-5793(80)80640-5.
5
A chloroplast-localized diaminopimelate decarboxylase in higher plants.高等植物中一种定位于叶绿体的二氨基庚二酸脱羧酶。
FEBS Lett. 1976 Apr 15;64(1):197-200. doi: 10.1016/0014-5793(76)80282-7.
6
Cadaverine--pyruvate transamination: the principal step of enzymatic quinolizidine alkaloid biosynthesis in Lupinus polyphyllus cell suspension cultures.尸胺 - 丙酮酸转氨基作用：多叶羽扇豆细胞悬浮培养物中喹诺里西啶生物碱酶促生物合成的主要步骤。
FEBS Lett. 1979 May 15;101(2):343-6. doi: 10.1016/0014-5793(79)81040-6.
Zotero 插件