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[持续性副流感病毒感染的建模]

[The modelling of a persistent parainfluenza infection].

作者信息

Ukbaeva T D, Karal'nik B V, Ismagulov A T

出版信息

Vopr Virusol. 1991 Sep-Oct;36(5):387-9.

PMID:1666475
Abstract

A model of parainfluenza persistent infection was developed in guinea pigs, based on the use of the suckling-adapted virus and an immunosuppressor cyclophosphan. The latter increased the titre of virus and its antigen and duration of their detection in the organs, but the dynamics of these findings was different, and also delayed the time of appearance and slightly prolonged the period of detection of antibody.

摘要

基于使用乳鼠适应病毒和免疫抑制剂环磷酰胺,在豚鼠中建立了副流感持续感染模型。后者增加了病毒及其抗原的滴度以及它们在器官中的检测持续时间,但这些结果的动态变化不同,并且还延迟了抗体出现的时间并略微延长了抗体检测的时间。

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