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加拿大海洛因供应的变化与澳大利亚海洛因短缺同时发生。

Changes in Canadian heroin supply coinciding with the Australian heroin shortage.

作者信息

Wood Evan, Stoltz Jo-Anne, Li Kathy, Montaner Julio S G, Kerr Thomas

机构信息

British Columbia Centre for Excellence in HIV/AIDS, St Paul's Hospital, Canada.

出版信息

Addiction. 2006 May;101(5):689-95. doi: 10.1111/j.1360-0443.2006.01385.x.

Abstract

AIMS

Previous studies have largely attributed the Australian heroin shortage to increases in local law enforcement efforts. Because western Canada receives heroin from similar source nations, but has not measurably increased enforcement practices or funding levels, we sought to examine trends in Canadian heroin-related indices before and after the Australian heroin shortage, which began in approximately January 2001.

METHODS

During periods before and after January 2001, we examined the number of fatal overdoses and ambulance responses to heroin-related overdoses that required the use of naloxone in British Columbia, Canada. As an overall marker of Canadian supply reduction, we also examined the quantity of heroin seized during this period. Lastly, we examined trends in daily heroin use among injection drug users enrolled in the Vancouver Injection Drug Users Study (VIDUS).

RESULTS

There was a 35% reduction in overdose deaths, from an annual average of 297 deaths during the years 1998-2000 in comparison to an average of 192 deaths during 2001-03. Similarly, use of naloxone declined 45% in the period coinciding with the Australian heroin shortage. Interestingly, the weight of Canadian heroin seized declined 64% coinciding with the Australian heroin shortage, from an average of 184 kg during 1998-2000 to 67 kg on average during 2001-03. Among 1587 VIDUS participants, the period coinciding with the Australian heroin shortage was associated independently with reduced daily injection of heroin [adjusted odds ratio: 0.55 (95% CI: 0.50-0.61); P < 0.001].

CONCLUSIONS

Massive decreases in three independent markers of heroin use have been observed in western Canada coinciding with the Australian heroin shortage, despite no increases in funding to Canadian enforcement efforts. Markedly reduced Canadian seizure activity also coincided with the Australian heroin shortage. These findings suggest that external global heroin supply forces deserve greater investigation and credence as a potential explanation for the Australian heroin shortage.

摘要

目的

以往研究大多将澳大利亚海洛因短缺归因于当地执法力度的加大。由于加拿大西部从类似的来源国获取海洛因,但执法措施或资金水平并未显著提高,我们试图研究在始于2001年1月左右的澳大利亚海洛因短缺前后加拿大与海洛因相关指标的趋势。

方法

在2001年1月前后,我们调查了加拿大不列颠哥伦比亚省致命过量用药的数量以及对需要使用纳洛酮的与海洛因相关过量用药的救护车响应情况。作为加拿大减少供应的总体指标,我们还调查了这一时期查获的海洛因数量。最后,我们研究了参与温哥华注射吸毒者研究(VIDUS)的注射吸毒者中每日海洛因使用量的趋势。

结果

过量用药死亡人数减少了35%,1998 - 2000年期间年均死亡297人,而2001 - 2003年期间平均为192人。同样,在与澳大利亚海洛因短缺同期,纳洛酮的使用量下降了45%。有趣的是,与澳大利亚海洛因短缺同时,加拿大查获的海洛因重量下降了64%,从1998 - 2000年期间的平均184千克降至2001 - 2003年期间的平均67千克。在1587名VIDUS参与者中,与澳大利亚海洛因短缺同期独立相关的是海洛因每日注射量减少[调整后的优势比:0.55(95%置信区间:0.50 - 0.61);P < 0.001]。

结论

在加拿大西部,尽管对执法工作的资金投入没有增加,但与澳大利亚海洛因短缺同时出现了海洛因使用的三个独立指标大幅下降的情况。加拿大查获活动的显著减少也与澳大利亚海洛因短缺同时发生。这些发现表明,全球外部海洛因供应力量作为澳大利亚海洛因短缺的一个潜在解释值得进行更深入的调查并给予更多信任。

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