Muganga N, Nkuadiolandu A, Mashako L M
Département de pédiatrie, cliniques universitaires, Kinshasa, République du Zaïre.
Pediatrie. 1991;46(12):825-9.
Clinical features observed in 60 cases of childhood HIV infection at the Cliniques Universitaires of Kinshasa is reported. Exposure mode, demonstrated in 92% of cases, was essentially maternofetal (65%) and related to blood transfusion (27%). The clinical signs appeared the first year of life in children born to seropositive mothers (82%). The main clinical features were: failure to thrive, high recurrent fever, persistent cough, chronic diarrhea, recurrent respiratory infections, hepatosplenomegaly, generalized lymphoadenopathy and oral candidiasis. Pulmonary lesions were very common (90%). These lesions were related to bacteria in 20 cases, to tuberculosis in 17 cases and to interstitial pneumonitis in 20 cases.
本文报告了在金沙萨大学诊所观察到的60例儿童HIV感染病例的临床特征。92%的病例显示了暴露模式，主要为母婴传播（65%）和输血相关（27%）。血清阳性母亲所生孩子在出生后第一年出现临床症状（82%）。主要临床特征为：发育不良、反复高热、持续性咳嗽、慢性腹泻、反复呼吸道感染、肝脾肿大、全身淋巴结肿大和口腔念珠菌病。肺部病变非常常见（90%）。这些病变在20例中与细菌有关，17例与结核有关，20例与间质性肺炎有关。
