Zuckerman Marc J, Nguyen Giang, Ho Hoi, Nguyen Luat, Gregory Gavin G
Texas Tech University Health Sciences Center, El Paso, Texas 79905, USA.
Dig Dis Sci. 2006 May;51(5):946-51. doi: 10.1007/s10620-005-9005-0. Epub 2006 May 3.
Prevalence estimates for irritable bowel syndrome from surveys in Western countries are 4.4% to 22%, generally higher in women than men, and only a minority seek health care. There are few studies of bowel patterns in Asian countries. We conducted a survey of a nonpatient population in Ho Chi Minh City, Vietnam, to determine bowel patterns and the prevalence of bowel dysfunction. A forced-choice, self-report questionnaire was distributed to 738 predominantly health care workers, as well as patient relatives, at Cho Ray Hospital in Ho Chi Minh City and returned by 411 (response rate of 55.7%). Results were analyzed for men and women using Student's t-test for continuous variables and chi-square test for categorical variables. Subjects were 53.6% female, with a mean age of 27.7+/-6.9 years. Overall perception of health was excellent/very good in 13.6%, good in 54.2%, and fair/poor in 32.1% (males, 17.1%, 51.3%, and 31.5%, vs. females, 10.6%, 56.7%, and 32.7%; P=NS). The mean number of stools reported per week was 6.5 (males, 6.6, vs. females, 6.4; P=NS) and ranged between 3 and 21 stools per week in 95.5%. The frequency of irritable bowel syndrome symptoms (using Rome I criteria) was 7.2% (95% CI=4.8-10.1), with males at 4.8% (95% CI=2.2-8.9) vs. females at 9.2% (95% CI=5.7-13.9) (P=0.08). Of the subjects with irritable bowel syndrome symptoms, 6 of 29 (20.7%) had seen a physician for bowel symptoms. There were no gender differences in reported infrequent stool (12.0%), frequent stool (11.3%), hard stool (17.5%), loose stool (6.5%), straining (14.5%), incomplete emptying (16.2%), bloating (15.0%), urgency (10.0%), or mucus (2.7%). In conclusion, this survey of a nonpatient population in Vietnam showed that irritable bowel syndrome symptoms as defined by Rome criteria were common and that there were no significant differences between sexes in either stool frequency or prevalence of irritable bowel syndrome, unlike previous studies from the United States. The prevalence of irritable bowel syndrome in Vietnam in this study was in the lower range of reported data from Western countries, possibly in part related to the use of the Rome criteria. Only a minority of subjects with irritable bowel syndrome symptoms reported seeking health care for these symptoms.
西方国家调查得出的肠易激综合征患病率估计为4.4%至22%，一般女性高于男性，只有少数患者寻求医疗保健。亚洲国家关于排便模式的研究较少。我们对越南胡志明市的非患者人群进行了一项调查，以确定排便模式和肠功能障碍的患病率。我们向胡志明市Cho Ray医院的738名主要为医护人员以及患者亲属发放了一份强制选择的自我报告问卷，411人回复（回复率为55.7%）。使用学生t检验分析连续变量的男性和女性结果，使用卡方检验分析分类变量的结果。受试者中53.6%为女性，平均年龄为27.7±6.9岁。总体健康感知为优秀/非常好的占13.6%，良好的占54.2%，一般/差的占32.1%（男性分别为17.1%、51.3%和31.5%，女性分别为10.6%、56.7%和32.7%；P=无显著差异）。报告的每周平均排便次数为6.5次（男性为6.6次，女性为6.4次；P=无显著差异），95.5%的人每周排便次数在3至21次之间。肠易激综合征症状（采用罗马I标准）的发生率为7.2%（95%可信区间=4.8 - 10.1），男性为4.8%（95%可信区间=2.2 - 8.9），女性为9.2%（95%可信区间=5.7 - 13.9）（P=0.08）。在有肠易激综合征症状的受试者中，29人中有6人（20.7%）因肠道症状看过医生。在报告的排便次数少（12.0%）、排便次数多（11.3%）、大便硬（17.5%）、大便稀（6.5%）、用力排便（14.5%）、排便不尽（16.2%）、腹胀（15.0%）、尿急（10.0%）或有黏液（2.7%）方面，男女之间没有差异。总之，这项对越南非患者人群的调查显示，按照罗马标准定义的肠易激综合征症状很常见，而且在排便频率或肠易激综合征患病率方面，男女之间没有显著差异，这与美国以往的研究不同。本研究中越南肠易激综合征的患病率处于西方国家报告数据的较低范围，这可能部分与采用罗马标准有关。只有少数有肠易激综合征症状的受试者报告因这些症状寻求医疗保健。
