Lu C-L, Chang F-Y, Lang H-C, Chen C-Y, Luo J-C, Lee S-D
Division of Gastroenterology, Taipei Veterans General Hospital, Taipei, Taiwan.
Aliment Pharmacol Ther. 2005 Jun 15;21(12):1497-505. doi: 10.1111/j.1365-2036.2005.02512.x.
Little is known about the gender effect on irritable bowel syndrome in Asia.
To assess the gender difference in Chinese subjects with irritable bowel syndrome meeting Rome II criteria.
Irritable bowel syndrome was identified from an apparently healthy adult population receiving a routine health maintenance program (n = 2018).
Female gender is not a factor associated with irritable bowel syndrome or irritable bowel syndrome-related health care-seeking behaviour. Female irritable bowel syndrome subjects, irrespective of consulting behaviour for irritable bowel syndrome, are likely to have < 3 bowel movements/week, hard/lumpy stools and abdominal fullness/bloating (P < 0.05). Female irritable bowel syndrome subjects are prone to be absent from school/work with more days of absenteeism, irrespective of consultation status (P < 0.05). Only female irritable bowel syndrome consulters have more absenteeism for their irritable bowel syndrome-related symptoms, reporting more sleep disturbances than their male counterparts (P < 0.001).
In an apparent healthy adult population in Taiwan, gender difference is present in Rome II defined Chinese subjects with irritable bowel syndrome as regards bowel symptoms, social impact and sleep quality. Female predominance was not found in irritable bowel syndrome subjects and irritable bowel syndrome-related health care-seeking behaviour in the current population. Both irritable bowel syndrome non-consulters and consulters have similar gender difference profiles in presenting symptoms, suggesting that bowel symptoms per se may not be the only factor leading to health care-seeking behaviour. The gender differences in sleep problems were observed solely in irritable bowel syndrome consulter.
在亚洲，关于性别对肠易激综合征的影响知之甚少。
评估符合罗马II标准的中国肠易激综合征患者的性别差异。
从接受常规健康维护计划的明显健康的成年人群（n = 2018）中识别出肠易激综合征患者。
女性并非与肠易激综合征或与肠易激综合征相关的就医行为相关的因素。女性肠易激综合征患者，无论其对肠易激综合征的咨询行为如何，每周排便次数可能少于3次，粪便硬/呈块状，并有腹部饱胀感（P < 0.05）。女性肠易激综合征患者更容易缺课/缺勤，缺勤天数更多，无论其咨询状态如何（P < 0.05）。只有女性肠易激综合征咨询者因与肠易激综合征相关的症状缺勤更多，报告的睡眠障碍比男性同行更多（P < 0.001）。
在台湾明显健康的成年人群中，符合罗马II标准的中国肠易激综合征患者在肠道症状、社会影响和睡眠质量方面存在性别差异。在当前人群中，肠易激综合征患者及与肠易激综合征相关的就医行为中未发现女性占主导地位。肠易激综合征非咨询者和咨询者在呈现症状方面具有相似的性别差异特征，这表明肠道症状本身可能不是导致就医行为的唯一因素。仅在肠易激综合征咨询者中观察到睡眠问题的性别差异。
