Yang Xiaoloin, Telama Risto, Viikari Jorma, Raitakari Olli T
LIKES Research Center, Jyväskylä, Finland.
Med Sci Sports Exerc. 2006 May;38(5):919-25. doi: 10.1249/01.mss.0000218121.19703.f7.
Maintaining a high level of physical activity throughout one's lifetime may decrease the risk of obesity. We evaluated how physical activity patterns from youths (9-18 yr) to adulthood are associated with body mass index (BMI) and waist circumference (WC) in a population of young adults.
As part of the longitudinal Cardiovascular Risk in Young Finns Study, we assessed physical activity over a 21-yr follow-up in a cohort of 1319 subjects. Physical activity was measured using a questionnaire completed in conjunction with a medical examination.
During the follow-up, 33.1% of men and 32.0% of women were classified as persistently active, and 11.5% of men and 7.4% of women as persistently inactive. Both decreasingly active and persistently inactive subjects were more likely to be obese as adults compared with persistently active subjects. In women, being decreasingly active from youth to adulthood compared with being persistently active was independently associated with the risk of being overweight (BMI = 25.0-29.9 kg.m(-2), odds ratio (OR) = 2.35, confidence interval (CI) = 1.16-4.78), obese (BMI > or = 30.0 kg.m(-2), OR = 2.72, CI = 1.04-7.09), mildly abdominally obese (WC = 800-879 mm, OR = 2.21, CI = 1.01-4.84), and severely abdominally obese (WC > or = 880 mm, OR = 2.19, CI = 1.03-4.67), after adjustment for several variables including childhood fatness. In men, decreasing physical activity during their lifetime was associated with mild (WC = 940-1019 mm, odds ratio (OR) = 1.78, CI = 1.00-3.19) and severe (WC > or = 1020 mm, OR = 2.47, CI = 1.27-4.78) abdominal obesity in unadjusted analyses, but these two associations disappeared after adjustment for confounding variables (OR = 1.51, CI = 0.72-3.17 and OR = 1.62, CI 0.66-4.02, respectively). In men, changes in physical activity were not associated with obesity or overweight as defined by cut-points of BMI.
Maintaining a high level of physical activity from youth to adulthood is independently associated with lower risk of abdominal obesity in among women, but not men. These findings suggest that changes in physical activity patterns during the lifetime may contribute to the development of abdominal obesity in women.
在一生中保持高水平的身体活动可能会降低肥胖风险。我们评估了在一群年轻成年人中，从青少年（9 - 18岁）到成年期的身体活动模式与体重指数（BMI）和腰围（WC）之间的关联。
作为芬兰青年人心血管风险纵向研究的一部分，我们在1319名受试者的队列中进行了21年的随访，评估身体活动情况。身体活动通过结合医学检查完成的问卷进行测量。
在随访期间，33.1%的男性和32.0%的女性被归类为持续活跃，11.5%的男性和7.4%的女性被归类为持续不活跃。与持续活跃的受试者相比，活动量逐渐减少和持续不活跃的受试者成年后更易肥胖。在女性中，与持续活跃相比，从青少年到成年期活动量逐渐减少与超重风险（BMI = 25.0 - 29.9 kg·m⁻²，优势比（OR） = 2.35，置信区间（CI） = 1.16 - 4.78）、肥胖风险（BMI≥30.0 kg·m⁻²，OR = 2.72，CI = 1.04 - 7.09）、轻度腹型肥胖风险（WC = 800 - 879 mm，OR = 2.21，CI = 1.01 - 4.84）以及重度腹型肥胖风险（WC≥880 mm，OR = 2.19，CI = 1.03 - 4.67）独立相关，在对包括儿童期肥胖在内的多个变量进行调整后依然如此。在男性中，未经调整的分析显示，一生中身体活动减少与轻度（WC = 940 - 1019 mm，优势比（OR） = 1.78，CI = 1.00 - 3.19）和重度（WC≥1020 mm，OR = 2.47，CI = 1.27 - 4.78）腹型肥胖相关，但在对混杂变量进行调整后，这两种关联消失（OR分别为1.51，CI = 0.72 - 3.17和OR = 1.62，CI = 0.66 - 4.02）。在男性中，身体活动的变化与BMI切点定义的肥胖或超重无关。
从青少年到成年期保持高水平的身体活动与女性腹型肥胖风险较低独立相关，但与男性无关。这些发现表明，一生中身体活动模式的变化可能有助于女性腹型肥胖的发生发展。
