Miller R B, Quinn P J
Can J Comp Med. 1975 Jul;39(3):270-90.
Fifty nonaborted and 50 aborted bovine foetuses were examined utilizing histology, immunoelectrophoresis, bacteriology and the fluorescent antibody technique. Lesions were observed in 12 of the nonaborted foesuses and in four of these immunoglobulins were demonstrated. In addition, two of the nonaborted foetuses had immunoglobulins in the absence of observed lesions. Lesions were observed in 48 of the aborted foetuses and immunoglobulins were detected in 22 of these. An etiological diagnosis was arrived at in 24 of the 50 aborted foetuses. The tissues most frequently observed to have lesions of diagnostic significance were eyelid, intestine, liver, lung and placenta. Intestinal lesions were observed in several foetuses in association with a variety of agents including infectious bovine rhinotracheitis. Foetuses diagnosed as aborting because of mycotic infection consistently displayed lesions in their eyelids. The value of taking eyelid sections in cases of suspected mycotic abortions, the significance of foetal intestinal lesions, the evaluation of abomasal aspirates and the diagnostic importance of immunoglobulin determinations in aborted foetuses are discussed.
利用组织学、免疫电泳、细菌学和荧光抗体技术对50例未流产和50例流产的牛胎儿进行了检查。在12例未流产胎儿中观察到病变,其中4例检测到免疫球蛋白。此外,2例未流产胎儿在未观察到病变的情况下检测到免疫球蛋白。在48例流产胎儿中观察到病变,其中22例检测到免疫球蛋白。50例流产胎儿中有24例得出了病因诊断。最常观察到具有诊断意义病变的组织是眼睑、肠道、肝脏、肺和胎盘。在几个胎儿中观察到肠道病变,与包括传染性牛鼻气管炎在内的多种病原体有关。因霉菌感染而诊断为流产的胎儿在眼睑中始终显示出病变。讨论了在疑似霉菌性流产病例中取眼睑切片的价值、胎儿肠道病变的意义、皱胃抽吸物的评估以及流产胎儿中免疫球蛋白测定的诊断重要性。