Ellis W A, Logan E F, O'Brien J J
Clin Exp Immunol. 1978 Jul;33(1):136-41.
The concentration of immunoglobulin classes G, M and A (IgG, IgM and IgA) in the sera of 233 aborted and 201 non-aborted foetuses was measured. IgM was first detected in a foetus at day 90 of gestation while IgG and IgA were first detected on day 111 of gestation. Immunoglobulins were detected in 81.5% of aborted foetuses and 32.8% of non-aborted foetuses. Total immunoglobulin concentrations of 20 mg/100 ml or greater were found in 35.2% of aborted foetuses but only in 4.5% of non-aborted foetuses. It is suggested that factors resulting in antigenic stimulation of the foetus may play an important part in bovine abortion.
对233例流产胎儿和201例未流产胎儿血清中的免疫球蛋白G、M和A(IgG、IgM和IgA)浓度进行了测定。妊娠90天时在胎儿中首次检测到IgM,而IgG和IgA在妊娠111天时首次检测到。在81.5%的流产胎儿和32.8%的未流产胎儿中检测到免疫球蛋白。20mg/100ml或更高的总免疫球蛋白浓度在35.2%的流产胎儿中发现,但仅在4.5%的未流产胎儿中发现。提示导致胎儿抗原刺激的因素可能在牛流产中起重要作用。