Consales G, Chelazzi C, Rinaldi S, De Gaudio A R
Anesthesiology and Resuscitation Unit, Department of Medical and Surgical Intensive Care, University of Florence, Careggi Hospital, Florence, Italy.
Minerva Anestesiol. 2006 May;72(5):329-36.
Continuous monitoring is of paramount importance in order to obtain a correct level of sedation in ICU patients. Clinical scoring systems, although simple and inexpensive, are often inadequate in evaluating the patient level of consciousness. Among instrumental tools for sedation monitoring, Bispectral Index (BIS) is now widely used due to its reliability and applicability. Nevertheless some doubts still exist regarding its usefulness in ICU.
Sedation, obtained with propofol or midazolam, was monitored with Ramsay scale and BIS in 40 patients admitted in ICU for postoperative monitoring after major abdominal or vascular surgery. A correlation between Ramsay score and BIS values was searched using Pearson test.
A good correlation between Ramsay score and BIS values was observed. At the deeper levels of sedation a wide range of BIS values corresponds to Ramsay score 6, indicating various levels of central nervous system depression that are not identified by clinical evaluation.
BIS monitoring is useful in ICU patients and allows a finest differentiation of sedation level in deeply sedated ICU patients.
持续监测对于在重症监护病房(ICU)患者中获得正确的镇静水平至关重要。临床评分系统虽然简单且成本低廉,但在评估患者意识水平方面往往不足。在用于镇静监测的仪器工具中,脑电双频指数(BIS)因其可靠性和适用性目前被广泛使用。然而,关于其在ICU中的实用性仍存在一些疑问。
对40例因腹部或血管大手术后入住ICU进行术后监测的患者,使用丙泊酚或咪达唑仑进行镇静,并采用Ramsay评分和BIS进行监测。使用Pearson检验寻找Ramsay评分与BIS值之间的相关性。
观察到Ramsay评分与BIS值之间有良好的相关性。在较深的镇静水平下,广泛的BIS值对应于Ramsay评分6,表明存在临床评估未识别出的不同程度的中枢神经系统抑制。
BIS监测对ICU患者有用,并能更精确地区分深度镇静的ICU患者的镇静水平。