Modi Avani C, Lim Crystal S, Yu Nami, Geller David, Wagner Mary H, Quittner Alexandra L
Cincinnati Children's Hospital Medical Center, Division of Behavioral Medicine and Clinical Psychology, 3333 Burnet Avenue, MLC-3015, Cincinnati, OH 45229, United States.
J Cyst Fibros. 2006 Aug;5(3):177-85. doi: 10.1016/j.jcf.2006.03.002. Epub 2006 May 5.
Adherence rates for chronic pediatric conditions are approximately 50%. The primary objective of the study was to assess rates of adherence using four different measurement methods for children with cystic fibrosis (CF).
Participants included 37 children with CF between 6 and 13 years of age and their primary caregivers. Adherence measures included parent and child self-reports, diary data, pharmacy refill history, and electronic monitors.
Results suggested that rates of adherence varied by treatment component and across measurement methods. However, when examining more objective measures, rates of overall adherence were below 50% for children with CF, indicating generally poor adherence to the treatment regimen. For example, rates of adherence to enzyme medications, using electronic and diary measures, ranged from 27% to 46%.
The multi-method measurement approach provided unique information regarding rates of adherence for each disease condition by type of treatment component. Accurately measuring rates of treatment adherence for children with CF is an important step in developing effective interventions to influence these behaviors.
儿科慢性病的依从率约为50%。本研究的主要目的是使用四种不同的测量方法评估囊性纤维化（CF）患儿的依从率。
参与者包括37名6至13岁的CF患儿及其主要照顾者。依从性测量方法包括家长和孩子的自我报告、日记数据、药房配药记录以及电子监测器。
结果表明，依从率因治疗成分和测量方法而异。然而，在检查更客观的测量方法时，CF患儿的总体依从率低于50%，这表明对治疗方案的依从性普遍较差。例如，使用电子和日记测量方法，酶类药物的依从率在27%至46%之间。
多方法测量方法提供了关于每种疾病状况按治疗成分类型划分的依从率的独特信息。准确测量CF患儿的治疗依从率是制定有效干预措施以影响这些行为的重要一步。
