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良性炎性神经疾病所致急性尿潴留

Acute urinary retention due to benign inflammatory nervous diseases.

作者信息

Sakakibara Ryuji, Yamanishi Tomonori, Uchiyama Tomoyuki, Hattori Takamichi

机构信息

Department of Neurology, Chiba University, 1-8-1 Inohana Chuo-ku, 260-8670 Chiba, Japan.

出版信息

J Neurol. 2006 Aug;253(8):1103-10. doi: 10.1007/s00415-006-0189-9. Epub 2006 May 6.

Abstract

Both neurologists and urologists might encounter patients with acute urinary retention due to benign inflammatory nervous diseases. Based on the mechanism of urinary retention, these disorders can be divided into two subgroups: disorders of the peripheral nervous system (e.g., sacral herpes) or the central nervous system (e.g., meningitis-retention syndrome [MRS]). Laboratory abnormalities include increased herpes virus titers in sacral herpes, and increased myelin basic protein in the cerebrospinal fluid (CSF) in some cases with MRS. Urodynamic abnormality in both conditions is detrusor areflexia; the putative mechanism of it is direct involvement of the pelvic nerves in sacral herpes; and acute spinal shock in MRS. There are few cases with CSF abnormality alone. Although these cases have a benign course, management of the acute urinary retention is necessary to avoid bladder injury due to overdistension. Clinical features of sacral herpes or MRS differ markedly from those of the original "Elsberg syndrome" cases.

摘要

神经科医生和泌尿科医生都可能会遇到因良性炎性神经疾病导致急性尿潴留的患者。根据尿潴留的机制,这些疾病可分为两个亚组:外周神经系统疾病(如骶部疱疹)或中枢神经系统疾病(如脑膜炎-尿潴留综合征[MRS])。实验室异常包括骶部疱疹中疱疹病毒滴度升高,以及部分MRS病例脑脊液(CSF)中髓鞘碱性蛋白升高。两种情况下的尿动力学异常均为逼尿肌无反射;其推测机制是骶部疱疹中盆腔神经直接受累,而MRS中为急性脊髓休克。单独出现脑脊液异常的病例很少。虽然这些病例病程良性,但急性尿潴留的处理对于避免膀胱过度扩张导致的损伤是必要的。骶部疱疹或MRS的临床特征与最初的“埃尔斯伯格综合征”病例明显不同。

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