Okunowo Adeyemi A, Ugwu Aloy O, Owie Emmanuel, Kolawole Habibat F, Adebayo Luqman A, Kusamotu Olaniyi A, Kuku Jubril O, Soibi-Harry Adaiah P, Ohazurike Ephraim O, Banjo Adekunbiola A F
Department of Obstetrics & Gynaecology, College of Medicine, University of Lagos/ Lagos University Teaching Hospital, Lagos, Nigeria.
Department of Obstetrics & Gynaecology, Lagos University Teaching Hospital (LUTH), Lagos, Nigeria.
Oxf Med Case Reports. 2020 Sep 22;2020(9):omaa081. doi: 10.1093/omcr/omaa081. eCollection 2020 Sep.
Primary vaginal leiomyosarcoma (VLMS) is an extremely rare variant of primary vaginal cancers with very poor prognosis irrespective of the stage at presentation and the type of treatment received. It is easily recurrent and has a high propensity for haematogenous spread especially to the lungs. We present the case of a 34-year-old Para 1 + 1 (1 alive) woman with recurrent vaginal mass of 8 years duration after two surgical excisions without histological evaluation. She had examination under anaesthesia and a wide local excision of the vaginal mass. Histological examination of the mass revealed poorly differentiated VLMS with positive surgical margins and she was commenced on adjuvant chemo-radiation. Histological evaluation remains the hallmark for diagnosing rare malignancies like VLMS, which unfortunately is not a standard practice in some resource-constraint settings.
原发性阴道平滑肌肉瘤（VLMS）是原发性阴道癌中一种极其罕见的变体，无论就诊时的分期和接受的治疗类型如何，其预后都非常差。它很容易复发，并且有很高的血行转移倾向，尤其是转移到肺部。我们报告了一例34岁、孕1产1（1个存活子女）的女性病例，该患者在两次手术切除后出现持续8年的复发性阴道肿物，但未进行组织学评估。她接受了麻醉下检查及阴道肿物的广泛局部切除。肿物的组织学检查显示为低分化VLMS，手术切缘阳性，随后她开始接受辅助放化疗。组织学评估仍然是诊断像VLMS这样罕见恶性肿瘤的标志，但不幸的是，在一些资源有限的环境中，这并不是一种标准做法。
