与星形胶质细胞携手搭建脊髓修复之桥。
Building bridges with astrocytes for spinal cord repair.
作者信息
Miller Robert H
机构信息
Department of Neurosciences, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106-4975, USA.
出版信息
J Biol. 2006;5(3):6. doi: 10.1186/jbiol40. Epub 2006 May 9.
Abstract
Simultaneous suppression of glial scarring and a general enhancement of axonal outgrowth has now been accomplished in an adult rat model of spinal cord transection. Transplantation of a novel astrocyte cell type derived from glial-restricted precursors in vitro raise the eventual possibility of cellular therapy for spinal cord injury.
摘要
在成年大鼠脊髓横断模型中，现已实现同时抑制胶质瘢痕形成并普遍促进轴突生长。体外移植源自胶质细胞限制前体细胞的新型星形胶质细胞类型，增加了脊髓损伤细胞治疗的最终可能性。
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