Torres René, Faini Francesca, Modak Brenda, Urbina Francisco, Labbé Cecilia, Guerrero Juan
Departamento de Ciencias del Ambiente, Fascultad de Química y Biología, Universidad de Santiago de Chile, Avda. Bernardo O'Higgins 3363, Santiago, Chile.
Phytochemistry. 2006 May;67(10):984-7. doi: 10.1016/j.phytochem.2006.03.016. Epub 2006 May 8.
The antioxidant activity of eight coumarins and two flavonols isolated from Haplopappus multifolius was studied with the DPPH radical method. Results show that a high concentration of phenolic coumarins and the presence of quercetin and rhamnetin in the exudates could account for the protection of the plant against oxidative stress. Structures for the coumarins 6-hydroxy-7-[(E,E)-3',7'-dimethyl-2',4',7'-octatrienyloxy] coumarin and 7-[(E)-3'-methyl-4'-hydroxy-2'-butenyloxy] coumarin are proposed on the basis of spectroscopic evidence.
采用DPPH自由基法研究了从多叶单冠菊中分离出的8种香豆素和2种黄酮醇的抗氧化活性。结果表明，渗出物中高浓度的酚类香豆素以及槲皮素和鼠李素的存在可以解释该植物对氧化应激的保护作用。基于光谱证据，提出了香豆素6-羟基-7-[(E,E)-3',7'-二甲基-2',4',7'-辛三烯氧基]香豆素和7-[(E)-3'-甲基-4'-羟基-2'-丁烯氧基]香豆素的结构。
