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该属：植物学、植物化学、传统用途及药理特性。

The genus : botany, phytochemistry, traditional uses, and pharmacological properties.

作者信息

Mitsi Christina, Echeverría Javier

机构信息

Departamento de Ciencias del Ambiente, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.

出版信息

Front Pharmacol. 2024 Oct 21;15:1490243. doi: 10.3389/fphar.2024.1490243. eCollection 2024.

DOI:10.3389/fphar.2024.1490243
PMID:39498337
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11532054/
Abstract

BACKGROUND

The genus Cass. [Asteraceae] comprises a large number of species distributed mainly in Chile and with various traditional medicinal uses.

PURPOSE

The present review addresses the botany, traditional uses, chemistry, biological and pharmacological activities of the genus, aiming to further potentiate the associated research and applications.

STUDY DESIGN AND METHODS

Literature data on the chemistry and bioactivity of the genus Haplopappus were mainly retrieved from digital databases such as SciFinder, PubMed, and Google Scholar, as well as from the scientific journal publishers' platforms linked with these databases.

RESULTS AND DISCUSSION

Although the majority of the botanical taxa of the genus has been understudied, available information is promising regarding its phytochemistry and bioactivity. A total of more than 400 compounds are present in different species, mostly terpenoids and phenolic compounds. Scientific literature supports various health promoting effects of extracts and isolated compounds, principally their effect against human pathogenic bacteria and their high antioxidant capacity. The existing limitations highlighted hereby are mainly associated to the lack of modern investigation regarding a wider number of species and chemical compounds, as well as to the absence of bioactivity results and clinical trials.

CONCLUSION

Scientific literature supports the ethnopharmacological, phytochemical and bioactive potential of the genus , however the aforementioned limitations need to be addressed in order to further promote and broaden both scientific research and future applications and uses.

摘要

背景

卡斯属（菊科）包含大量主要分布在智利的物种，并具有多种传统药用用途。

目的

本综述阐述了该属的植物学、传统用途、化学、生物学及药理活性，旨在进一步加强相关研究与应用。

研究设计与方法

关于单冠毛菊属化学和生物活性的文献数据主要从诸如科学网、医学期刊数据库和谷歌学术等数字数据库，以及与这些数据库相关联的科学期刊出版商平台获取。

结果与讨论

尽管该属的大多数植物分类群研究不足，但现有信息显示其植物化学和生物活性颇具前景。不同物种中共存在400多种化合物，主要是萜类化合物和酚类化合物。科学文献支持提取物和分离化合物具有多种促进健康的作用，主要是它们对人类病原菌的作用及其高抗氧化能力。此处强调的现有局限性主要与缺乏对更多物种和化合物的现代研究，以及缺乏生物活性结果和临床试验有关。

结论

科学文献支持该属的民族药理学、植物化学和生物活性潜力，然而需要解决上述局限性，以进一步促进和拓宽科学研究及未来的应用与用途。

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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b5d/11532054/ece97758a0e6/fphar-15-1490243-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b5d/11532054/2f5702672585/fphar-15-1490243-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b5d/11532054/8c168e7d1f74/fphar-15-1490243-g009.jpg
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