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胃蛋白酶对二羟基铝碳酸钠、水滑石和甘羟铝盐酸中和动力学的影响。

Effect of pepsin on the kinetics of HCl neutralization by dihydroxyaluminum sodium carbonate, hydrotalcite and dihydroxyaluminum aminoacetate.

作者信息

Kokot Z J

机构信息

Department of Inorganic and Analytical Chemistry, School of Medicine, Poznań, Poland.

出版信息

Acta Pol Pharm. 1991;48(3-4):27-31.

PMID:1669540
Abstract

The rate of HCl neutralization by dihydroxyaluminum sodium carbonate (DHASC), hydrotalcite (HT) and dihydroxyaluminum aminoacetate (DHAAA) in the presence of different amount of pepsin (PP) has been studied at constant pH = 3.0. The results can be explained using Weibull distribution function by comparing the kinetical parameters with and without the substance added and as a function of their concentration. Some aspects of mechanisms of inhibition or acceleration of acid neutralization of DHASC, HT and DHAAA by PP are also discussed.

摘要

在恒定pH = 3.0的条件下,研究了碳酸二羟基铝钠(DHASC)、水滑石(HT)和氨基乙酸二羟基铝(DHAAA)在不同量胃蛋白酶(PP)存在下对盐酸的中和速率。通过比较添加和不添加该物质时的动力学参数及其浓度函数,可用威布尔分布函数解释结果。还讨论了PP对DHASC、HT和DHAAA酸中和抑制或加速机制的一些方面。

相似文献

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Acta Pol Pharm. 1991;48(3-4):27-31.
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