Chandra Naveen, Pandey Susmita, Suryawanshi S N, Gupta Suman
Division of Medicinal Chemistry, Central Drug Research Institute, Lucknow 226001, India.
Eur J Med Chem. 2006 Jun;41(6):779-85. doi: 10.1016/j.ejmech.2006.02.004. Epub 2006 May 12.
Some aryl substituted terpenyl pyrimidines 4 (a-p) have been synthesized using novel synthetic methods. The compounds were screened for in vitro antileishmanial activity against promastigotes. Compounds 4c, 4i and 4l showed IC(50) values as 35, 35 and 25 microg ml(-1).
一些芳基取代的萜烯基嘧啶4（a - p）已采用新型合成方法合成。对这些化合物进行了体外抗前鞭毛体利什曼原虫活性筛选。化合物4c、4i和4l的半数抑制浓度（IC50）值分别为35、35和25微克/毫升。
