从大西洋鳕鱼（Gadus morhua L.）分离出的杀鲑气单胞菌C2菌株O抗原寡糖的结构研究

Structural studies of the O-antigenic oligosaccharide from Vibrio salmonicida strain C2 isolated from Atlantic cod, Gadus morhua L.

作者信息

Bøgwald Jarl, Hoffman James

机构信息

Norwegian College of Fishery Science, University of Tromsø, Norway.

出版信息

Carbohydr Res. 2006 Aug 14;341(11):1965-8. doi: 10.1016/j.carres.2006.04.016. Epub 2006 May 15.

DOI:10.1016/j.carres.2006.04.016

PMID:16697993

Abstract

We report the chemical structure of the oligosaccharide part of Vibrio salmonicida lipopolysaccharide serotype C2, isolated from Atlantic cod (Gadus morhua L.). The structure was established by NMR spectroscopy and mass spectrometry. It is concluded that the oligosaccharide has the following structure in which L-alpha-D-Hepp is L-glycero-alpha-D-manno-heptopyranose, D-alpha-D-Hepp is D-glycero-alpha-D-manno-heptopyranose, alpha-NonA is 5-acetamidino-7-acetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-D-galacto-nonulosonic acid, and PEA is phosphoethanolamine. [chemical structure: see text]

摘要

我们报道了从大西洋鳕鱼（Gadus morhua L.）中分离出的杀鲑气单胞菌血清型C2脂多糖寡糖部分的化学结构。该结构通过核磁共振光谱和质谱确定。得出的结论是，该寡糖具有以下结构，其中L-α-D-Hepp是L-甘油-α-D-甘露庚糖，D-α-D-Hepp是D-甘油-α-D-甘露庚糖，α-NonA是5-脒基-7-乙酰氨基-3,5,7,9-四脱氧-L-甘油-α-D-半乳糖壬糖醛酸，PEA是磷酸乙醇胺。[化学结构：见正文]