Park Jeong-Sook, Kim Gee-Young, Han Kun
College of Pharmacy, Chungbuk National University, Cheongju, Heungdukgu Gaeshindong San 12, Chungbuk 361-763, South Korea.
J Ethnopharmacol. 2006 Oct 11;107(3):349-53. doi: 10.1016/j.jep.2006.03.039. Epub 2006 Apr 18.
This study examined the possibility of using Shilajit as a fertility agent. The effects of Shilajit on spermatogenesis and ovogenesis were studied using male and female rats. Shilajit was administered orally to 7-week-old rats over a 6-week period. In the male rats, the number of sperms in the testes and epididymides was significant higher than in the control. A histological examination revealed an apparent increase in the number of seminiferous tubular cell layers in the testes of the treated rats. However, there were no significant differences in the weights of heart, spleen, liver, kidney, brain, testes and epididymides. In the female rats, the effect of Shilajit was estimated by the ovulation inducing activity. Over a 5-day, ovulation was induced in seven out of nine rats in the Shilajit administration group and in three out of nine rats in the control. It was estimated that Shilajit had both a spermiogenic and ovogenic effect in mature rats.
本研究考察了使用希拉季特作为生育剂的可能性。利用雄性和雌性大鼠研究了希拉季特对精子发生和卵子发生的影响。在6周的时间里，对7周龄的大鼠口服希拉季特。在雄性大鼠中，睾丸和附睾中的精子数量显著高于对照组。组织学检查显示，处理过的大鼠睾丸中曲细精管细胞层数明显增加。然而，心脏、脾脏、肝脏、肾脏、大脑、睾丸和附睾的重量没有显著差异。在雌性大鼠中，通过排卵诱导活性评估希拉季特的作用。在5天的时间里，希拉季特给药组9只大鼠中有7只诱导排卵，对照组9只大鼠中有3只诱导排卵。据估计，希拉季特对成熟大鼠具有生精和生卵作用。
