Tinsley Colin R, Bille Emmanuelle, Nassif Xavier
Microbiologie et Génétique Moléculaire, UMR1238 INRA/INA-PG/CNRS, Institut National Agronomique Paris-Grignon, 78850 Thiverval-Grignon, France.
Microbes Infect. 2006 Apr;8(5):1365-71. doi: 10.1016/j.micinf.2005.12.013. Epub 2006 Mar 15.
An increasing number of pathogenicity factors carried by bacteriophages have been discovered. This review considers bacteriophage-bacterium interaction and its relation to disease processes. We discuss the search for new bacteriophage-associated pathogenicity factors, with emphasis on recent advances brought by the use of genomic sequence data and the techniques of genomic epidemiology.
越来越多由噬菌体携带的致病因素被发现。本综述探讨了噬菌体与细菌的相互作用及其与疾病过程的关系。我们讨论了寻找新的噬菌体相关致病因素,重点是利用基因组序列数据和基因组流行病学技术带来的最新进展。