Postnov A, Zarowski A, De Clerck N, Vanpoucke F, Offeciers F E, Van Dyck D, Peeters S
Department of Physics, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
Acta Otolaryngol. 2006 May;126(5):467-74. doi: 10.1080/00016480500437377.
X-ray microtomography (micro-CT) is a new technique allowing for visualization of the internal structure of opaque specimens with a quasi-histological quality. Among multiple potential applications, the use of this technique in otology is very promising. Micro-CT appears to be ideally suited for in vitro visualization of the inner ear tissues as well as for evaluation of the electrode damage and/or surgical insertion trauma during implantation of the cochlear implant electrodes. This technique can greatly aid in design and development of new cochlear implant electrodes and is applicable for temporal bone studies. The main advantage of micro-CT is the practically artefact-free preparation of the samples and the possibility of evaluation of the interesting parameters along the whole insertion depth of the electrode. This paper presents the results of the first application of micro-CT for visualization of the inner ear structures in human temporal bones and for evaluation of the surgical positioning of the cochlear implant electrodes relative to the intracochlear soft tissues.
X射线显微断层扫描(显微CT)是一项新技术,能够以类似组织学的质量呈现不透明标本的内部结构。在众多潜在应用中,该技术在耳科学中的应用前景十分广阔。显微CT似乎非常适合对内耳组织进行体外成像,以及评估人工耳蜗电极植入过程中的电极损伤和/或手术插入创伤。这项技术能够极大地助力新型人工耳蜗电极的设计与研发,适用于颞骨研究。显微CT的主要优势在于样本制备几乎无伪影,并且能够沿着电极的整个插入深度评估感兴趣的参数。本文展示了首次将显微CT应用于人类颞骨内耳结构成像以及评估人工耳蜗电极相对于耳蜗内软组织的手术定位的结果。