Bassiouny H K, Al-Maktari M T
Department of Tropical Health, High Institute of Public Health, University of Alexandria, Alexandria, Egypt.
East Mediterr Health J. 2005 Jul;11(4):606-17.
To investigate the consequences of maternal malaria during late pregnancy, we conducted a preliminary study in the 2 hospitals in Al Hodeidah on 276 women who had uncomplicated vaginal deliveries. Only 17 women had malaria (Plasmodium falciparum), 6 with peripheral parasitaemia and 11 with both peripheral parasitaemia and placental malaria. Coincident infection carried a 9.44 times higher risk of preterm delivery and a 12.2 times greater risk of low birth weight (< 2500 g). Anaemia was diagnosed in 46.4%, associated with malaria in 11.7% of cases. All risk factors, rural residence (OR 5.18), maternal age < 20 years (OR 4.93) and primigravidae (OR 8.29), were significantly associated with malaria infection.
为了研究妊娠晚期孕妇患疟疾的后果，我们在荷台达的两家医院对276名顺产的妇女进行了一项初步研究。只有17名妇女患有疟疾（恶性疟原虫），6名有外周血寄生虫血症，11名既有外周血寄生虫血症又有胎盘疟疾。合并感染导致早产风险高9.44倍，低出生体重（<2500克）风险高12.2倍。46.4%的孕妇被诊断为贫血，其中11.7%的病例与疟疾有关。所有风险因素，即农村居住（比值比5.18）、母亲年龄<20岁（比值比4.93）和初产妇（比值比8.29），均与疟疾感染显著相关。
