Kumagai S G, Rosales R F, Hunter G C, Rappaport W D, Witzke D B, Chvapil T A, Chvapil M, Sutherland J C
Department of Surgery, University Medical Center, Tucson, Arizona 85724.
Am J Surg. 1991 Dec;162(6):620-2; discussion 622-3. doi: 10.1016/0002-9610(91)90122-t.
This study compared the healing of midline fascial incisions made with either scalpel or electrocautery and inoculated with Escherichia coli in 57 Sprague-Dawley rats. At 7 days, tensile strength was significantly less when incisions were made with electrocautery than with a scalpel. Additionally, would strength was inversely related to the concentration of the inoculum of E coli. The use of electrocautery was also associated with more frequent bacteremia at 48 hours and higher mortality at 7 days. Our results suggest that the technique used to incise the abdominal fascia influences subsequent wound healing, particularly in contaminated wounds.
本研究比较了在57只斯普拉格-道利大鼠中,使用手术刀或电灼术制作中线筋膜切口并接种大肠杆菌后的愈合情况。在第7天时,用电灼术制作切口时的抗张强度显著低于使用手术刀时。此外,伤口强度与大肠杆菌接种物的浓度呈负相关。使用电灼术还与48小时时更频繁的菌血症和7天时更高的死亡率相关。我们的结果表明,用于切开腹部筋膜的技术会影响随后的伤口愈合,尤其是在污染伤口中。