García Borrás Silvia, Diez Cristina, Cotorruelo Carlos, Pellizon Oscar, Biondi Claudia, Beloscar Juan, Bottasso Oscar, Racca Amelia
Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario Suipacha 531, 2000 Rosario, Argentina.
Ann Clin Biochem. 2006 May;43(Pt 3):214-6. doi: 10.1258/000456306776865205.
DNA typing of human lymphocyte antigen (HLA)-dicloro-1-[beta]-D-ribofuranosyl-benzimidazole 1 (DRB1) alleles in 35 individuals serologically positive for T. cruzi and in 41 healthy controls was performed. DRB10409 allele was significantly more prevalent in seropositive individuals, with a trend being also observed for the DRB10701 and DRB1*1503 alleles. Although statistically insignificant, the latter was found more frequent in cases with cardiomyopathy.
对35名克氏锥虫血清学阳性个体和41名健康对照者进行了人类白细胞抗原（HLA）-二氯-1-[β]-D-呋喃核糖基苯并咪唑1（DRB1）等位基因的DNA分型。DRB10409等位基因在血清阳性个体中显著更常见，DRB10701和DRB1*1503等位基因也观察到这种趋势。尽管在统计学上无显著意义，但后者在心肌病患者中更常见。
