Adamiia N A, Zhorzholiani L D, Mandzhavidze N Sh, Kherkheulidze M N, Chanturaiia N N
Georgian Med News. 2006 Apr(133):74-7.
Purpose of the work was to investigate clinical-allergic peculiarities of allergic rhinitis, together with bronchial asthma in school-age children. There were studied random representative group of children, in total 3000 subjects from 6 to 17. According to the results of epidemiological research in school-age children's population, prevalence of allergic rhinitis was 13,2%. In 19,1% of cases, allergic rhinitis was accompanied with bronchial asthma and in 8% of the patients there was indicated bronchial spasm of physical load (verified as clinically, also through the test with physical load), coughing version of asthma was observed in 4,5% of children. Thus, in children with allergic rhinitis, within the structure of clinical versions (by the criteria of severity) of rare bronchial asthma prevailed (69,8%, among which 65% - intermitting form and 4,8% - persisting form), without statistically significant difference between the boys and girls. Combination of inherited predisposition to allergy with the atopic dermatitis, in the in the anamnesis of children with the increased level of general IgE in the blood serum may be considered as early diagnostic predictor of atopic phenotype as for the allergic rhinitis, also for its combination with the bronchial asthma.
这项工作的目的是研究学龄儿童过敏性鼻炎合并支气管哮喘的临床过敏特点。对一组随机抽取的有代表性的儿童进行了研究，共计3000名6至17岁的受试者。根据对学龄儿童群体的流行病学研究结果，过敏性鼻炎的患病率为13.2%。在19.1%的病例中，过敏性鼻炎伴有支气管哮喘，8%的患者存在运动负荷诱发的支气管痉挛（通过临床及运动负荷试验证实），4.5%的儿童出现咳嗽型哮喘。因此，在过敏性鼻炎患儿中，少见的支气管哮喘临床类型（按严重程度标准）占主导（69.8%，其中65%为间歇型，4.8%为持续型），男孩和女孩之间无统计学显著差异。在血清总IgE水平升高的儿童既往史中，过敏遗传易感性与特应性皮炎的结合可被视为过敏性鼻炎及其合并支气管哮喘特应性表型的早期诊断预测指标。
