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[儿童支气管哮喘中的变应性共病]

[Allergic comorbidities in bronchial asthma, in children].

作者信息

Rugină Aurica, Rusu Tania, Ioniuc Ileana

机构信息

Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină.

出版信息

Rev Med Chir Soc Med Nat Iasi. 2010 Jul-Sep;114(3):633-7.

Abstract

Bronchial asthma is the most frequent chronic disease of childhood. The association of this disease with allergic rhinitis increases the prevalence and severity of bronchial asthma to 60% compared with 2% in subjects without allergic rhinitis. Food allergy can be expressed in a variety of respiratory symptoms, especially when IgE mediated immune responses are involved. In children, the prevalence of bronchial asthma associated with food induced atopic eczema is 2-8% and respiratory clinical picture can be a component of the multisystem anaphylactic reaction or of chronic respiratory disease like bronchial asthma, serous otitis. The association of other allergic comorbidities, like sinusitis, ocular allergies, lymphoid hypertrophy, sleep obstructive apnoea, leads to the conclusion that allergic bronchial asthma (extrinsic) is a systemic disease, with onset at any age, and the dominant clinical feature depends on the child's genetic pattern.

摘要

支气管哮喘是儿童最常见的慢性疾病。与过敏性鼻炎相关联,使得支气管哮喘的患病率和严重程度相较于无过敏性鼻炎的受试者增加至60%,而后者仅为2%。食物过敏可表现为多种呼吸道症状,尤其是当涉及IgE介导的免疫反应时。在儿童中,与食物诱发的特应性皮炎相关的支气管哮喘患病率为2% - 8%,呼吸道临床表现可能是多系统过敏反应的一部分,或者是慢性呼吸道疾病如支气管哮喘、浆液性中耳炎的一部分。其他过敏性合并症,如鼻窦炎、眼部过敏、淋巴样肥大、睡眠呼吸暂停综合征,这些情况表明过敏性支气管哮喘(外因性)是一种全身性疾病,可在任何年龄发病,其主要临床特征取决于儿童的遗传模式。

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