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中药艾灸联合柳氮磺胺吡啶及甲氨蝶呤治疗强直性脊柱炎——附30例报告

Treatment of ankylosing spondylitis with medicated moxibustion plus salicylazosulfapyridine and methotrexate--a report of 30 cases.

作者信息

Jia Jie, Wang Qiyin, Zhang Tiehan, Li Jun

机构信息

The Third Hospital Affiliated to Xinxiang Medical College, Xinxiang, Henan 453003, China.

出版信息

J Tradit Chin Med. 2006 Mar;26(1):26-8.

Abstract

OBJECTIVE

To evaluate the therapeutic effect of medicated moxibustion plus administration of salicylazosulfapyridine (SASP) and methotrexate (MTX) for treatment of active ankylosing spondylitis (AS).

METHOD

Ninety cases of active AS were randomly assigned to Group A, B and C (N = 30 in each group), and treated respectively with SASP and MTX, acupuncture plus SASP and MTX, and composite sulfur (tablet) moxibustion plus SASP and MTX for 3 successive courses (2 months each course with an interval of 5 days).

RESULTS

Improvement in sacroiliitis index, Schober test, occipital wall test, finger-ground distance, as well as the erythrocyte sedimentation rate (ESR) and the content of C-reactive protein (CRP) in Group B and C was far superior to that of Group A (P < 0.01).

CONCLUSION

Combined use of western medicine with acupuncture or with medicated moxibustion produces a better therapeutic effect than western medicine given alone.

摘要

目的

评价药物艾灸联合柳氮磺胺吡啶(SASP)及甲氨蝶呤(MTX)治疗活动期强直性脊柱炎(AS)的疗效。

方法

将90例活动期AS患者随机分为A、B、C组(每组30例),分别给予SASP及MTX、针刺联合SASP及MTX、复方硫磺(片)灸联合SASP及MTX治疗,连续治疗3个疗程(每个疗程2个月,间隔5天)。

结果

B组和C组的骶髂关节炎指数、Schober试验、枕墙试验、指地距以及红细胞沉降率(ESR)和C反应蛋白(CRP)含量的改善情况远优于A组(P<0.01)。

结论

西药联合针刺或药物艾灸治疗活动期强直性脊柱炎的疗效优于单纯西药治疗。

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