Yin Guodong, Zhou Baohan, Meng Xianggao, Wu Anxin, Pan Yuanjiang
Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, Central China Normal University, Wuhan, PRC.
Org Lett. 2006 May 25;8(11):2245-8. doi: 10.1021/ol060541e.
[reaction: see text] A novel and efficient carbon-carbon double-bond formation reaction via coupling of aryl or heteroaryl methyl ketones has been developed. A dimethyl sulfoxide-iodine-CuO system was proven to be efficient for this reaction and afforded the expected products in good yields. A new synthetic strategy, a self-sorting tandem reaction, was involved in this type of reaction and was presented for the first time.
