van Aalst J, Beuls E A M, Cornips E M J, Vanormelingen L, Vandersteen M, Weber J W, Vles J S H
Department of Neurosurgery, University Hospital Maastricht, P. Debyelaan 25, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.
Childs Nerv Syst. 2006 Oct;22(10):1307-15. doi: 10.1007/s00381-006-0106-7. Epub 2006 May 18.
Cases of infected dermal sinus are scarce and detailed surgical anatomical descriptions are hardly found in literature. The clinical, radiological, and surgical findings in four cases of an infected dermal sinus located at the lower spine are presented to elucidate the pathological anatomical configuration.
The first case showed two dermal sinuses with a parallel course extra- and intradurally, ending in a confluence of cavities connected to the conus. In this case, as well as in the fourth case, the signs and symptoms were those of meningitis. The second case presented with meningitis and a subdural empyema, while the third case presented with an intradermoid-intramedullary abscess at the junction between the DS and the conus. This child probably showed signs and symptoms of conus involvement as early as during pregnancy.
The anatomy of the nervous elements in this congenital anomaly is heavily disturbed, more particularly in case of infection, due to extensive arachnoidal scarring. The latter renders dissection laborious and recognition of anatomical details difficult, resulting in complete excision of a dermal sinus in less than half of the cases. Despite their variability in presentation, most cases of an infected dermal sinus show similar characteristic features.
感染性皮样窦病例罕见,文献中几乎没有详细的手术解剖描述。本文报告4例位于下脊柱的感染性皮样窦的临床、影像学和手术所见,以阐明其病理解剖结构。
第1例显示两个皮样窦,在硬膜外和硬膜内平行走行,终止于与圆锥相连的腔隙汇合处。在该病例以及第4例中,体征和症状均为脑膜炎表现。第2例表现为脑膜炎和硬膜下积脓,而第3例在皮样窦与圆锥交界处出现皮样囊肿-髓内脓肿。该患儿早在孕期可能就已出现圆锥受累的体征和症状。
在这种先天性异常中,神经结构的解剖受到严重干扰,尤其是在感染情况下,这是由于广泛的蛛网膜瘢痕形成所致。后者使解剖操作费力,难以识别解剖细节,导致不到半数的病例能够完整切除皮样窦。尽管其表现各异,但大多数感染性皮样窦病例具有相似的特征。