Prakash P, Kasaby H E, Aggarwal R K, Humfrey S
Department of Ophthalmology, Southend Hospital NHS Trust, Prittlewell Chase, Westcliff on Sea, Essex, UK.
Eye (Lond). 2007 Feb;21(2):177-82. doi: 10.1038/sj.eye.6702153. Epub 2006 May 19.
To prospectively assess the efficacy of bimanual phacoemulsification and implantation of Thinoptx, an injectable intraocular lens (IOL), inserted through 1.70 mm clear corneal incision.
Department of Ophthalmology, Southend Hospital NHS Trust, UK.
A total of 50 eyes of 49 randomly selected patients with cataracts had microincision clear corneal bimanual phacoemulsification (MICS) with implantation of Thinoptx IOL in the capsular bag. All patients underwent full preoperative assessment. Postoperative assessment was carried out at 3 and 6 weeks and at 15 months.
In all 50 cases the IOL was inserted through 1.70 mm clear corneal incision. The mean best-corrected visual acuity was 0.02 (6/6-1) at 6 weeks and was 0.17 (6/10) at the final follow-up. The mean final surgically induced astigmatism at 6 weeks was 0.0106. Coloured haloes around artificial lights were perceived by 69.23% of patients at 6 weeks and by 61.29% at the final follow-up. One patient underwent IOL exchange for this. Posterior capsular opacification was noticed in 31.26% at 6 weeks and in 64.51% at 15 months. Anterior capsular opacification was noticed in 5.26% at 6 weeks and in 16.12% at 15 months. In one patient the IOL had to be exchanged because of tilt and displacement of the IOL due to anterior capsular phimosis.
We conclude Thinoptx can be safely inserted through 1.70 mm incision used for bimanual phacoemulsification. Distance and near visual acuity achieved with this IOL is satisfactory. There is no significant change in keratometric astigmatism following this procedure. However, posterior capsular opacification rate was significantly higher with this IOL. Haloes around light sources were significant.
前瞻性评估双手操作超声乳化术联合植入通过1.70mm透明角膜切口插入的可注射人工晶状体(IOL)Thinoptx的疗效。
英国绍森德医院国民保健服务信托基金眼科。
49例随机选择的白内障患者的50只眼接受了微切口透明角膜双手操作超声乳化术(MICS),并在囊袋内植入Thinoptx人工晶状体。所有患者均接受了全面的术前评估。术后在3周、6周和15个月时进行评估。
所有50例患者的人工晶状体均通过1.70mm透明角膜切口植入。6周时平均最佳矫正视力为0.02(6/6-1),最终随访时为0.17(6/10)。6周时平均最终手术诱导散光为0.0106。6周时69.23%的患者感觉到人工光源周围有彩色光晕,最终随访时为61.29%。1例患者因此接受了人工晶状体置换。6周时31.26%的患者出现后囊膜混浊,15个月时为64.51%。6周时5.26%的患者出现前囊膜混浊,15个月时为16.12%。1例患者因前囊膜挛缩导致人工晶状体倾斜和移位而不得不更换人工晶状体。
我们得出结论,Thinoptx可通过用于双手操作超声乳化术的1.70mm切口安全植入。使用该人工晶状体获得的远视力和近视力令人满意。该手术后角膜散光无显著变化。然而,该人工晶状体的后囊膜混浊率明显更高。光源周围的光晕明显。