Ozyürekoğlu Tuna, McCabe Steven J, Goldsmith L Jane, LaJoie A Scott
Division of Hand Surgery, Department of Surgery, School of Medicine, University of Louisville, Louisville, KY 40202, USA.
J Hand Surg Am. 2006 May-Jun;31(5):733-8; discussion 739-40. doi: 10.1016/j.jhsa.2006.01.012.
To identify the change score in the Symptom Severity Scale (SSS) of the Carpal Tunnel Syndrome (CTS) Questionnaire that is associated with an important change in clinical status.
Twenty-eight patients with CTS treated with a carpal tunnel steroid injection completed the Brigham and Women's Hospital CTS Questionnaire before steroid injections and at the 3-week follow-up visit. Satisfaction was determined by postcare review of the clinical management. To calculate the minimal clinically important difference, receiver operating characteristic curves were created. The area under the curve was calculated to determine and compare the responsiveness of the entire SSS and the pain and sensory questions in isolation.
The SSS of the CTS Questionnaire, including its pain and sensory domain, can show a meaningful clinical improvement after carpal tunnel injection. The SSS, its sensory domain, and its pain domain were statistically better than chance. All 3 measures showed predictive ability; however, the total SSS was the most sensitive in detecting a change. The minimal clinically important difference in the score of the SSS after carpal tunnel steroid injection was found to be 1.04.
The SSS can be used to distinguish a clinically important change after carpal tunnel injection. A decrease of 1.04 or more in the SSS score may indicate a clinically important change in a patient's state of health.
TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic, Level I.
确定腕管综合征（CTS）问卷症状严重程度量表（SSS）中的变化分数，该分数与临床状态的重要变化相关。
28例接受腕管类固醇注射治疗的CTS患者在类固醇注射前及3周随访时完成了布莱根妇女医院CTS问卷。通过对临床管理的护理后评估来确定满意度。为计算最小临床重要差异，绘制了受试者工作特征曲线。计算曲线下面积以确定并比较整个SSS以及单独的疼痛和感觉问题的反应性。
CTS问卷的SSS，包括其疼痛和感觉领域，在腕管注射后可显示出有意义的临床改善。SSS及其感觉领域和疼痛领域在统计学上优于随机情况。所有这三项测量均显示出预测能力；然而，总SSS在检测变化方面最敏感。发现腕管类固醇注射后SSS评分的最小临床重要差异为1.04。
SSS可用于区分腕管注射后的临床重要变化。SSS评分降低1.04或更多可能表明患者健康状态的临床重要变化。
研究类型/证据水平：预后性研究，I级。
