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经胆道镜直视下螺旋水刀治疗肝内胆管结石30例报告

The treatment of intrahepatic calculosis by applying helix hydro-jet lithotripsy under video choledochoscope: a report of 30 cases.

作者信息

Wu Yi-Wu, Jian Yong-Ping, Liang Jian-Shen, Zhong Wei, Yang Zhi-Wei

机构信息

The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong, 519000, PR China.

出版信息

Langenbecks Arch Surg. 2006 Aug;391(4):355-8. doi: 10.1007/s00423-006-0058-0. Epub 2006 May 20.

Abstract

BACKGROUND AND AIMS

Intrahepatic lithiasis is a common disease in southeast Asia [Sheen-Chen and Chou, Acta Chir Scand 156:387-390, 1990], and a difficult problem of biliary surgery. There is no established method of treating patients with intrahepatic stones [Uchiyama et al., Arch Surg 137:149-533, 2002]. In recent years, resection of the affected liver lobe or segment is the best therapeutic option to completely remove the source of recurrent infection. The need for endoscopic treatment modalities is evident because hepatic resections are combined with a high morbidity and mortality rate [Andersson et al., HPB Surg 2:145-147, 1990; Adamek et al., Scand J Gastroenterol 34:1157-1161, 1999]. Hepatic resection only fit the cases in which the stones localized in one lobe or segment, while it doesn't fit the cases which have polystones in left and right biliary tract. Duodenoscope can only get the stones in the common bile duct and cannot deal with the intrahepatic lithiasis. The management of intrahepatic lithiasis can only be treated by intraoperative or postoperative choledochoscope. For big stones or compact stones, lithotripsy should be applied. But the laser lithotripsy and the electrohydraulic lithotripsy can cause serious complications such as perforation of bile duct. It needs a safer and more reliable treatment for intrahepatic lithiasis. The aim of our work is to study the lithotrity treatment of intrahepatic lithiasis by using helix hydro-jet under Video Choledochoscope.

MATERIALS AND METHODS

From March 31, 2003 to October 20, 2004, 30 intrahepatic stone patients were treated. Eighteen of them were women and 12 were men, with ages ranging from 35 to 80 years (mean, 58 years). According to B ultrasound and computed tomography (CT) scan report, there were five cases of intrahepatic lithiasis and common bile duct stones, 25 cases of left and right hepatic duct stones, and one case with giant intrahepatic stone (1.5 x 1.5 x 1.2 cm). Intraoperative or postoperative choledochoscopic helix hydro-jet lithotripsy was applied through a video choledochoscope. For the patients to have the intraoperative choledochoscopic helix hydro-jet lithotripsy, they should be diagnosed correctly by B ultrasound or CT scan. The biliary tract reconstruction by spiral CT scan is as helpful as MRCP or ERCP for clinical diagnosis. For the patients to have the postoperative choledochoscopic helix hydro-jet lithotripsy, they should be diagnosed correctly by T-tube cholangiography and BUS and CT scan. All patients should be verified without stones remaining in the bile duct after lithotripsy by choledochoscopic examination and T-tube cholangiography, and should be examined by BUS again after 6 months to 1 year. We decide whether complications occurred by observation of symptoms and signs after choledochoscopy and lithotripsy.

RESULTS

Seventy-five intrahepatic stones with diameter ranging from 0.6 to 1.5 cm were successfully fragmentized in 30 patients using of helix hydro-jet lithotripsy. These fragmentized stones mainly are bilirubin stones. The lithotripsy was carried for 45 times and the procedure needs 1-1.5 h. Helix hydro-jet lithotripsy are used in 16 cases during operation and 12 cases after operation; two cases during operation and after operation. Intrahepatic calculosis was cleaned out completely and verified by postoperative choledochoscope examination and postoperative T-tube cholangiography examination. No complications were observed.

CONCLUSION

Helix hydro-jet lithotripsy under video choledochoscope is a safe and effective method for the removal of intrahepatic stone. No bile duct damnified and perforation was observed. The procedure is without pain and heat, and the pressure can be adjusted easily. The research provides a new way of using the helix hydro-jet, and a new way of curing the intrahepatic lithiasis.

摘要

背景与目的

肝内胆管结石是东南亚地区的一种常见疾病[Sheen-Chen和Chou,《斯堪的纳维亚外科杂志》156:387 - 390,1990年],也是胆道外科的一个难题。目前尚无成熟的肝内胆管结石治疗方法[Uchiyama等人,《外科学文献》137:149 - 533,2002年]。近年来,切除受累肝叶或肝段是彻底消除反复感染源的最佳治疗选择。由于肝切除手术的发病率和死亡率较高[Andersson等人,《HPB外科》2:145 - 147,1990年;Adamek等人,《斯堪的纳维亚胃肠病学杂志》34:1157 - 1161,1999年],因此内镜治疗方式的需求十分明显。肝切除仅适用于结石局限于一个肝叶或肝段的病例,而不适用于左右肝管均有多发结石的情况。十二指肠镜只能取出胆总管内的结石,无法处理肝内胆管结石。肝内胆管结石的治疗只能通过术中或术后胆道镜进行。对于较大或紧密的结石,应采用碎石术。但激光碎石术和液电碎石术可能会导致严重并发症,如胆管穿孔。肝内胆管结石需要一种更安全、更可靠的治疗方法。我们研究的目的是探讨在电子胆道镜下使用螺旋水刀治疗肝内胆管结石的碎石治疗方法。

材料与方法

2003年3月31日至2004年10月20日,对30例肝内胆管结石患者进行了治疗。其中女性18例,男性12例,年龄35至80岁(平均58岁)。根据B超和计算机断层扫描(CT)报告,5例为肝内胆管结石合并胆总管结石,25例为左右肝管结石,1例为巨大肝内结石(1.5×1.5×1.2 cm)。通过电子胆道镜进行术中或术后胆道镜螺旋水刀碎石术。对于接受术中胆道镜螺旋水刀碎石术的患者,应通过B超或CT扫描进行正确诊断。螺旋CT扫描进行胆道重建对临床诊断的帮助与磁共振胰胆管造影(MRCP)或内镜逆行胰胆管造影(ERCP)相当。对于接受术后胆道镜螺旋水刀碎石术的患者,应通过T管胆管造影、B超和CT扫描进行正确诊断。所有患者在碎石术后经胆道镜检查和T管胆管造影证实胆管内无结石残留,并在术后半年至1年再次进行B超检查。我们通过观察胆道镜检查和碎石术后的症状和体征来判断是否发生并发症。

结果

使用螺旋水刀碎石术成功将30例患者的75枚直径为0.6至1.5 cm的肝内胆管结石击碎。这些碎结石主要为胆红素结石。共进行碎石45次,手术过程需要1 - 1.5小时。术中使用螺旋水刀碎石术16例,术后使用12例;术中及术后均使用2例。术后经胆道镜检查和T管胆管造影检查证实肝内结石已完全清除。未观察到并发症。

结论

电子胆道镜下螺旋水刀碎石术是一种安全有效的肝内胆管结石清除方法。未观察到胆管损伤和穿孔。该手术无痛、无热,压力可轻松调节。本研究为螺旋水刀的应用提供了一种新方法,也为肝内胆管结石的治疗提供了一种新途径。

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