Moore John E, Barton Mary D, Blair Iain S, Corcoran Deborah, Dooley James S G, Fanning Séamus, Kempf Isabelle, Lastovica Albert J, Lowery Colm J, Matsuda Motoo, McDowell David A, McMahon Ann, Millar B Cherie, Rao Juluri R, Rooney Paul J, Seal Bruce S, Snelling William J, Tolba Ola
Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, Northern Ireland, UK.
Microbes Infect. 2006 Jun;8(7):1955-66. doi: 10.1016/j.micinf.2005.12.030. Epub 2006 Mar 31.
Antibiotic resistance, particularly with the fluoroquinolones and macrolide antibiotics, has now emerged globally with thermophilic campylobacters, including Campylobacter jejuni and C. coli, giving rise to concerns about how these organisms have acquired such resistance characteristics, as well as consequences for human and animal treatment. This review examines (i) the clinical epidemiology of antibiotic resistance in human and animal thermophilic campylobacters, (ii) an update on resistance rates globally, (iii) surveillance of antimicrobial resistance in campylobacters originating from animals, particularly poultry, (iv) the role of the environment in the acquisition and transmission of antibiotic-resistant campylobacters, as well as (v) issues of biocide resistance in campylobacters.
抗生素耐药性，尤其是氟喹诺酮类和大环内酯类抗生素的耐药性，目前已在全球范围内出现在嗜热弯曲杆菌中，包括空肠弯曲杆菌和大肠弯曲杆菌，这引发了人们对这些微生物如何获得此类耐药特性以及对人类和动物治疗产生的后果的担忧。本综述探讨了：（i）人类和动物嗜热弯曲杆菌抗生素耐药性的临床流行病学；（ii）全球耐药率的最新情况；（iii）对来自动物，特别是家禽的弯曲杆菌的抗菌药物耐药性监测；（iv）环境在抗生素耐药弯曲杆菌的获得和传播中的作用；以及（v）弯曲杆菌中的杀生物剂耐药性问题。
