抗微生物耐药性岛：沙门氏菌染色体和质粒中的耐药基因簇
Antimicrobial resistance islands: resistance gene clusters in Salmonella chromosome and plasmids.
作者信息
Miriagou Vivi, Carattoli Alessandra, Fanning Séamus
机构信息
Laboratory of Bacteriology, Hellenic Pasteur Institute, Athens, Greece.
出版信息
Microbes Infect. 2006 Jun;8(7):1923-30. doi: 10.1016/j.micinf.2005.12.027. Epub 2006 Mar 29.
PMID:16716633
Abstract
Genes conferring simultaneous resistance to different classes of antimicrobials, confer a selective advantage to the host, particularly when those corresponding antibiotics are administered. Multiple resistance genes clustered within the same genetic locus (resistance island) can be transferred en bloc to other organisms. In this chapter we review novel multidrug resistance islands recently described in Salmonella.
摘要
赋予对不同种类抗菌药物同时耐药性的基因，会给宿主带来选择性优势，尤其是在使用相应抗生素的时候。聚集在同一基因位点（耐药岛）内的多个耐药基因可以整体转移到其他生物体中。在本章中，我们将综述最近在沙门氏菌中发现的新型多重耐药岛。
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