Choi Marc H, MacKenzie John D, Dalinka Murray K
Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street/1 Silverstein, Philadelphia, PA 19104, USA.
Rheum Dis Clin North Am. 2006 May;32(2):427-46, viii. doi: 10.1016/j.rdc.2006.04.001.
Crystal-induced arthropathies constitute a spectrum of inflammatory arthritides that is induced by cellular reaction to crystal deposition in and around joints. A variety of microcrystals may be deposited and can induce an inflammatory response. The three most common types of crystal-induced arthropathy are gout, calcium pyrophosphate dihydrate deposition disease, and calcium hydroxyapatite deposition disease. Each has a characteristic clinical presentation, crystal type that may be aspirated from affected tissues, and radiographic appearance. Each of these entities may occur as a primary abnormality or secondary to an underlying disorder. Sometimes these diseases may coexist in the same joint or individual. Imaging frequently plays a crucial role in the diagnosis of crystal-induced arthropathies and may help to monitor disease progression and treatment response.
晶体诱导性关节病是一类炎症性关节炎,由细胞对关节内及周围晶体沉积的反应所诱发。多种微晶可能会沉积并引发炎症反应。晶体诱导性关节病最常见的三种类型是痛风、二水焦磷酸钙沉积病和羟基磷灰石钙沉积病。每种类型都有其特征性的临床表现、可从受累组织吸出的晶体类型以及影像学表现。这些病症中的每一种都可能作为原发性异常出现,或继发于潜在疾病。有时,这些疾病可能在同一关节或个体中共存。影像学检查在晶体诱导性关节病的诊断中常常起着关键作用,并且可能有助于监测疾病进展和治疗反应。