Ghalayani Parichehr, Tavakoli Payam, Eftekhari Mehdi, Haghighi Mohammad Akhondzadeh
Turk Patoloji Derg. 2015;31(1):60-3. doi: 10.5146/tjpath.2014.01223.
Focal epithelial hyperplasia or Heck's disease is an infrequent asymptomatic condition caused by human papillomavirus types 13 or 32 affecting the mucous membrane of the mouth and is commonly seen in young individuals. Firstly, it was described in Indians and Eskimos, but it exists in various populations. We present three cases of Heck's disease in an Afghan immigrant family group living in Iran that seem to have familial predominance. The disease was identified as oral focal epithelial hyperplasia on the basis of histopathologic and clinical findings. The lesions were reduced significantly after 4 months of good oral hygiene. Dentists should be familiar with the clinical manifestations of these types of lesions that affect the oral cavity. In fact, histopathologic assessment and clinical observation are necessary to establish the diagnosis.
局灶性上皮增生或赫克病是一种由13型或32型人乳头瘤病毒引起的、影响口腔黏膜的罕见无症状疾病，常见于年轻人。该疾病首先在印第安人和爱斯基摩人中被描述，但在不同人群中均有存在。我们报告了居住在伊朗的一个阿富汗移民家族群体中的3例赫克病病例，似乎存在家族性优势。根据组织病理学和临床发现，该疾病被诊断为口腔局灶性上皮增生。经过4个月良好的口腔卫生护理后，病变明显减轻。牙医应熟悉这些影响口腔的病变的临床表现。事实上，组织病理学评估和临床观察对于确诊是必要的。
