De Briel D, Langs J C, Rougeron G, Chabot P, Le Faou A
Institut de Bactériologie, Strasbourg, France.
J Hosp Infect. 1991 Jan;17(1):35-43. doi: 10.1016/0195-6701(91)90075-j.
During an 11-month prospective study, urine cultures were performed on 5685 samples obtained in three hospital units. The use of a selective medium improved the recovery of antibiotic-multiresistant corynebacteria (AMC): 703 isolates (12.4%) compared with 88 isolates (1.6%) on sheep blood agar. Corynebacterium group D2 (CGD2) was isolated in 80.5% of urines yielding greater than or equal to 10(5) AMC ml-1 whereas Corynebacterium jeikeium represented 80.2% of isolates with less than 10(5) AMC ml-1. Among 16 patients with greater than or equal to 10(5) ml-1 C. jeikeium none had signs of urinary tract infection. In contrast, among 56 patients with greater than or equal to 10(5) CGD2, 40 (71%) had abnormal urinary sediment (mainly apatite or struvite crystals) and 29 (52%) had clinical signs of urinary tract infections sometimes complicated by lithiasis (seven cases) and alkaline-encrusted cystitis (two cases).
在一项为期11个月的前瞻性研究中，对三个医院科室采集的5685份样本进行了尿培养。使用选择性培养基提高了多重耐药棒状杆菌（AMC）的回收率：在选择性培养基上分离出703株（12.4%），而在羊血琼脂上仅分离出88株（1.6%）。在每毫升尿液中AMC数量大于或等于10⁵的样本中，80.5%分离出D2群棒状杆菌（CGD2），而在每毫升尿液中AMC数量少于10⁵的分离株中，杰氏棒状杆菌占80.2%。在16例每毫升尿液中杰氏棒状杆菌数量大于或等于10⁵的患者中，无一例有尿路感染迹象。相比之下，在56例每毫升尿液中CGD2数量大于或等于10⁵的患者中，40例（71%）尿沉渣异常（主要为磷灰石或鸟粪石晶体），29例（52%）有尿路感染的临床症状，有时并发结石（7例）和碱性结痂性膀胱炎（2例）。
