Shalabi M M, Gortemaker A, Van't Hof M A, Jansen J A, Creugers N H J
Department of Periodontology and Biomaterials, Dentistry 309, College of Dental Science, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
J Dent Res. 2006 Jun;85(6):496-500. doi: 10.1177/154405910608500603.
A systematic review was performed on studies investigating the effects of implant surface roughness on bone response and implant fixation. We searched the literature using MEDLINE from 1953 to 2003. Inclusion criteria were: (1) abstracts of animal studies investigating implant surface roughness and bone healing; (2) observations of three-month bone healing, surface topography measurements, and biomechanical tests; (3) provision of data on surface roughness, bone-to-implant contact, and biomechanical test values. The literature search revealed 5966 abstracts. There were 470, 23, and 14 articles included in the first, second, and third selection steps, respectively. Almost all papers showed an enhanced bone-to-implant contact with increasing surface roughness. Six comparisons were significantly positive for the relationship of bone-to-implant contact and surface roughness. Also, a significant relation was found between push-out strength and surface roughness. Unfortunately, the eventually selected studies were too heterogeneous for inference of data. Nevertheless, the statistical analysis on the available data provided supportive evidence for a positive relationship between bone-to-implant contact and surface roughness.
我们针对研究种植体表面粗糙度对骨反应及种植体固定效果影响的相关研究进行了一项系统综述。我们使用MEDLINE对1953年至2003年的文献进行了检索。纳入标准为：（1）关于研究种植体表面粗糙度与骨愈合的动物研究摘要；（2）对三个月骨愈合情况、表面形貌测量及生物力学测试的观察；（3）提供表面粗糙度、骨与种植体接触情况及生物力学测试值的数据。文献检索共得到5966篇摘要。在第一轮、第二轮和第三轮筛选步骤中分别纳入了470篇、23篇和14篇文章。几乎所有论文都表明，随着表面粗糙度增加，骨与种植体的接触增强。骨与种植体接触情况和表面粗糙度之间的六项比较结果呈显著正相关。此外，推出强度与表面粗糙度之间也存在显著关系。遗憾的是，最终选定的研究在数据推断方面异质性过大。尽管如此，对现有数据的统计分析为骨与种植体接触情况和表面粗糙度之间的正相关关系提供了支持性证据。
