Mosquera María del Mar, Sanz Juan Carlos, Echevarría Juan Emilio, Herranz Nieves, Fernández Marisa, de Ory Fernando
Servicio de Microbiología Diagnóstica, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Ctra. de Majadahonda-Pozuelo s/n, 28220 Majadahonda, Madrid, Spain.
Enferm Infecc Microbiol Clin. 2006 Apr;24(4):251-3. doi: 10.1016/s0213-005x(06)73771-5.
Nowadays, most exanthematic diseases for which a vaccine is available affect young adults. A large percentage of these cases prove to be rubella. The aim of this study is to assess the performance of specific IgM and RT-PCR for the diagnosis of rubella infection. Fifty-nine patients with clinically suspected measles or rubella, and with available serum, whole blood, urine and pharyngeal exudate specimens were studied. RT-PCR in pharyngeal exudate was found to be the most effective marker at the start of the disease (mean, 2.5 days). IgM detection yielded a larger percentage of positive results (76.2%), but at a later time (3.7 days).
如今，大多数有疫苗可用的发疹性疾病都影响年轻人。这些病例中很大一部分被证实为风疹。本研究的目的是评估特异性IgM和RT-PCR在风疹感染诊断中的性能。对59例临床疑似麻疹或风疹且有血清、全血、尿液和咽部分泌物标本的患者进行了研究。发现咽部分泌物中的RT-PCR在疾病开始时（平均2.5天）是最有效的标志物。IgM检测产生的阳性结果百分比更高（76.2%），但时间较晚（3.7天）。
