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[对埃洛犬种双行睫患病率的分析]

[Analysis of the prevalence of distichiasis in the dog breed Elo].

作者信息

Kaufhold Judith, Hamann Henning, Steinbach Gudrun, Gordon Sabine, Brahm Rolf, Grussendorf Heinrich, Rosenhagen Carsten U, Distl Ottmar

机构信息

Institut für Tierzucht und Vererbungsforschung, Tierärztlichen Hochschule Hannover.

出版信息

Berl Munch Tierarztl Wochenschr. 2006 May-Jun;119(5-6):233-7.

PMID:16729470
Abstract

The Elo is a recently established dog breed in which the eye anomaly distichiasis has been frequently observed. Out of a total of 234 Elo dogs ophthalmologically examined over four years, 27.8% of the dogs showed between 1 and 31 distichia. There were twice as many distichia in the upper than in the lower eyelid. Litter size, the number of examinations of Elo dogs per ophthalmologist and the proportion of genes of the Eurasian dog had a significant influence on the prevalence of distichiasis. The error probability for the inbreeding coefficient and the proportion of genes of the Old English Sheepdog were just above the significance limit of p = 0.05. No significance was found for the remaining effects. Heritability for distichiasis was estimated using a linear animal model. After transformation of the linear observed estimate onto the underlying liability scale the heritability estimate was h2 = 0.43.

摘要

Elo是最近培育出的一种犬种,其中经常观察到眼部异常双行睫。在四年间接受眼科检查的234只Elo犬中,27.8%的犬有1至31根双行睫。上眼睑的双行睫数量是下眼睑的两倍。窝产仔数、每位眼科医生检查Elo犬的次数以及欧亚犬基因比例对双行睫的患病率有显著影响。近亲繁殖系数和古代英国牧羊犬基因比例的误差概率略高于p = 0.05的显著性界限。其余因素未发现显著性。使用线性动物模型估计双行睫的遗传力。将线性观察估计值转换到潜在易感性量表上后,遗传力估计值为h2 = 0.43。

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Genomic analysis and prediction of genomic values for distichiasis in Staffordshire bull terriers.斯塔福郡斗牛梗犬双行睫的基因组分析及基因组值预测
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2
Heritability estimates of distichiasis in Staffordshire bull terriers using pedigrees and genome-wide SNP data.使用系谱和全基因组 SNP 数据估计斯塔福郡斗牛梗的双行睫遗传率。
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